摘要
目的研究分析急性心肌梗死(AMI)患者介入(PCI)术后新发室性心律失常(NOVA)的相关因素。方法选取2022年3月至2023年3月我院心血管内科收治的AMI行PCI手术患者125例为研究对象,根据术后动态心电监测NOVA发生情况,分为NOVA组及非NOVA组,各37、88例。收集患者一般资料与临床资料,记录PCI术中慢血流/无复流情况,采血检测超敏C反应蛋白(hs-CRP)、总胆固醇(TC)、肌酐、肾小球滤过率(e GFR)、尿酸、肌酸激酶同工酶(CK-MB)及肌钙蛋白I(Tn I),行心脏彩超测量左室射血分数(LVEF),分析影响NOVA的相关因素。结果单因素研究显示年龄、慢血流例数、肌酐、尿酸、CK-MB、Tn I水平及LVEF比较有差异(P<0.05);多因素Logistic回归分析显示年龄、慢血流、CK-MB及Tn I水平为影响NOVA的独立危险因素(P<0.05)。结论年龄、慢血流、CK-MB及TnI水平均为影响AMI患者PCI术后发生NOVA的独立危险因素,对具备相关危险因素的患者要重点关注。
Objective To analyze the related factors of new-onset ventricular arrhythmia(NOVA)in patients with acute myocardial infarction(AMI)after percutaneous coronary intervention(PCI).Methods 125 patients with AMI who underwent PCI in the hospital from March 2022 to March 2023 were selected as the research subjects.According to the occurrence of NOVA on postoperative ambulatory electrocardiographic monitoring,they were divided into NOVA and non-NOVA groups,with 37 and 88 cases in each group.Collection of general and clinical information on patients.The situation of slow flow/no reflow during PCI was recorded.Hypersensitive C-reactive protein(hs-CRP),total cholesterol(TC),creatinine,glomerular filtration rate(eGFR),uric acid,creatine kinase isoenzyme(CK-MB),and troponin I(TnI)were detected,cardiac ultrasound was performed to measure left ventricular ejection fraction(LVEF),and relevant factors affecting NOVA were analysed.Results Univariate analysis found that there were statistically significant differences in age,number of patients with slow flow,creatinine,uric acid,CK-MB and TnI levels,and LVEF(P<0.05).Multivariate Logistic regression analysis found that age,slow flow,CK-MB and TnI levels were independent risk factors for NOVA(P<0.05).Conclusion Age,slow flow,CK-MB and TnI levels are independent risk factors for NOVA in patients with AMI after PCI.Special attention should be paid to patients with above-mentioned risk factors.
作者
王真真
张海波
李运丽
WANG Zhen-zhen;ZHANG Hai-bo;LI Yun-li(Cardiology Department,The First Affliated Hospital of Henan University,Kaifeng 475000,Henan Province,China)
出处
《罕少疾病杂志》
2024年第11期56-57,共2页
Journal of Rare and Uncommon Diseases
基金
河南省开封市科技发展计划项目(1903048)。
关键词
急性心肌梗死
介入术
新发室性心律失常
相关因素
Acute Myocardial Infarction
Percutaneous Coronary Intervention
New-onset Ventricular Arrhythmia
Related Factor
