摘要
目的:回顾性研究高血栓负荷的急性心肌梗死(acute myocardial infarction,AMI)患者血栓抽吸后并延迟植入支架的效果。方法:从186例AMI患者中选取56例血栓积分评分≥2分的患者纳入本研究。根据血栓抽吸后的血栓积分评分分为2组,血栓积分评分0～1分为即刻支架组,经血栓抽吸3次后血栓积分评分仍≥2分者为延迟支架组。采用TIMI分级和TIMI心肌灌注(TMP)分级对2组患者的冠脉血流和心肌灌注进行比较。结果:支架植入后TIMI积分即刻支架组低于延迟组,但差异无统计学意义(P=0.07);而TMP积分即刻支架组显著低于延迟支架组,差异有统计学意义(P<0.05)。结论:对于高血栓负荷的AMI患者在经血栓抽吸仍有高血栓负荷者,经强化抗栓处理后延迟行支架植入可更好地改善患者的心肌灌注。
Objective To retrospectively evaluate the efficacy of stent-delayed implantation in patients with acute myocardial infarction（AMI） with high thrombus burden after thrombus extraction was performed.Methods Of 186 consecutive AMI patients,56 were included according to thrombus score（TS）≥2,and then were divided into 2 groups based on the thrombus score after thrombus extraction was executed： the stent-direct implantation group（TS=0 or 1）and the stent-delayed implantation group（TS≥2） even if 3 times thrombus extraction were given.Thrombolysis in myocardial infarction（TIMI）flow grade and TIMI myocardial perfusion（TMP） were used to assess the coronary artery flow and myocardial perfusion,respectively.Results TIMI score in the stent-direct implantation group was lower than that in the stent-delayed implantation group.There was no significant difference（P=0.07）.TMP score in the stent-direct implantation group was significantly lower than that in the stent-delayed implantation group（P〈0.05）.Conclusion Stent-delayed implantation can remarkably improve myocardial perfusion in AMI patients with high thrombus burden after thrombus extraction and intensive anti-thrombosis therapy is administrated.
出处
《中南大学学报（医学版）》
CAS
CSCD
北大核心
2010年第5期483-486,共4页
Journal of Central South University ：Medical Science
关键词
冠状动脉疾病
经皮冠状动脉介入术
血栓
心肌灌注
延迟行支架植入
coronary disease
percutaneous coronary interventions
thrombus
myocardial perfusion
stent-delayed implantation
