摘要
目的探讨大学生屏幕静坐时间与血脂异常的关系,为青少年血脂异常防控提供依据。方法选取湖北省某高校2021年新入学大学生作为研究对象,于当年9~10月进行问卷调查和体检。通过问卷收集过去一年受访者平均每天的屏幕静坐时间,并通过体检获得被研究者身高、体重、血压等指标,检测血脂(总胆固醇、甘油三酯、低密度脂蛋白、高密度脂蛋白)、血糖等生化指标。采用二元Logistic回归、限制性立方样条、亚组分析等方法分析静坐与血脂异常之间的关联。结果共纳入3383名大学生,平均屏幕静坐时间为(4.44±2.29)h/d,598例血脂异常,血脂异常患病率为17.68%,其中胆固醇升高、甘油三酯升高、低密度脂蛋白升高以及高密度脂蛋白降低的患病率分别为4.76%、3.72%、4.29%、7.06%。血脂异常人群平均屏幕静坐时间为(4.60±2.21)h/d,长于血脂正常人群平均屏幕静坐时间(4.41±2.30)h/d,但差异无统计学意义(P=0.062)。二元Logistic回归分析显示,在校正性别、年龄、BMI、高血压病史等相关因素后,大学生屏幕静坐时间与血脂异常呈正相关,以屏幕静坐时间<2 h/d为参考,屏幕静坐时间为2 h/d~、4 h/d~、6 h/d~者血脂异常的OR(95%CI)值分别为1.44[95%CI(1.00,2.07)]、1.62[95%CI(1.13,2.32)]、1.59[95%CI(1.10,2.29)]。大学生屏幕静坐时间与总血脂异常之间存在线性相关(P-overall=0.028,P-nonlinear=0.113)。亚组分析结果显示,大学生屏幕静坐时间与血脂异常的相关性在女性、血压正常人群及非超重肥胖人群中更加明显。结论较长的屏幕静坐时间可能与大学生血脂异常的风险增加有关,尤其在女性人群中更为明显,其因果关联还需进一步大样本、前瞻性研究予以验证。
Objective To explore the relationship between screen-based sedentary time and dyslipidemia among college students,and to provide a basis for the prevention and control of dyslipidemia in adolescents.Methods Newly enrolled college students from a university in Hubei province in September 2021 were selected for the study,and a questionnaire survey and physical examination were conducted from September to October of the same year.The average daily screen sitting time of the respondents in the past year was collected through questionnaires.The height,weight,blood pressure and other indexes were obtained through physical examination,and the biochemical indexes of blood lipids(triglyceride,total cholesterol,low-density lipoprotein,high-density lipoprotein)and blood glucose were detected.Binary Logistic regression,restricted cubic spline and subgroup analysis were used to analyze the association between sedentary time and dyslipidemia.Results A total of 3,383 college students were included,with an average screen-based sedentary time of(4.44±2.29)h/d.There were 598 cases of dyslipidemia among college students,and the overall prevalence of dyslipidemia was 17.68%.The prevalence of elevated cholesterol,elevated triglycerides,elevated low-density lipoprotein,and decreased high-density lipoprotein were 4.76%,3.72%,4.29%,and 7.06%,respectively.The mean screen-based sedentary time in the dyslipidemia population was(4.60±2.21)h/d,which was longer than the mean screen-based sedentary time in the normolipidemic population(4.41±2.30)h/d,but the difference was not statistically significant(P=0.062).Binary Logistic regression analysis showed that dyslipidemia in college students was positively correlated with screen-based sedentary time after correcting for relevant factors such as gender,age,BMI,and history of hypertension,with screen-based sedentary time<2 h/d as the reference,and the OR(95%CI)of dyslipidemia in subjects with sedentary screen time of 2 h/d~,4 h/d~,6 h/d~were 1.44(1.00,2.07),1.62(1.13,2.32),1.59(1.10,2.29),respe
作者
吴涓
王艳
章进
贺明慧
何婉红
罗玉双
顾祎寒
郑晨阳
刘艳丽
王静
WU Juan;WANG Yan;ZHANG Jin;HE Minghui;HE Wanhong;LUO Yushuang;GU Yihan;ZHENG Chenyang;LIU Yanli;WANG Jing(School of Public Health,Hubei University of Medicine,Shiyan 442000,Hubei Province,China;Health Center for Environment and Health in Water Source-to-North Diversion,Hubei University of Medicine,Shiyan 442000,Hubei Province,China;Department of Laboratory,Shiyan Guoyao Dongfeng General Hospital,Shiyan 442001,Hubei Province,China;Department of Endocrinology,Hubei Medical University Affiated People's Hospital,Shiyan 442000,Hubei Province,China)
出处
《医学新知》
CAS
2024年第10期1079-1088,共10页
New Medicine
基金
国家自然科学基金面上项目(81872698,71774049)
湖北省高等学校优秀中青年科技创新团队计划(JYT2021024)
“十四五”湖北省高等学校优势特色学科群(公共卫生与健康)(2022PHXKQ3)
湖北医药学院附属国药东风总医院青年人才项目(2022Q22)。
关键词
屏幕暴露
屏幕静坐时间
血脂异常
横断面研究
青少年
大学生
相关性
Screen exposure
Screen-based sedentary time
Dyslipidemia
Crosssectional studies
Adolescent
College student
Association
