摘要
目的 分析妊娠早期气血亏虚证先兆流产患者应用阿胶珠结合黄体酮治疗的效果。方法 选取2022年7月至2023年12月江西省妇幼保健院收治的72例妊娠早期先兆流产患者为研究对象,均符合中医气血亏虚证诊断标准,采用随机数字表法将其分为对照组(36例)观察组(36例)。对照组采用单一黄体酮治疗,观察组采用阿胶珠结合黄体酮治疗,比较两组患者中医证候积分、激素水平、保胎成功率及不良反应发生率。结果 治疗前两组患者的中医证候积分、激素水平比较,差异无统计学意义(P>0.05),治疗后观察组中医证候积分低于对照组,观察组血清雌二醇(E_(2))水平、人绒毛膜促性腺激素(HCG)水平、保胎成功率高于对照组,差异有统计学意义(P<0.05);治疗后,两组患者孕酮激素(P)水平比较,差异无统计学意义(P>0.05);观察组不良反应总发生率低于对照组,差异有统计学意义(P<0.05)。结论 阿胶珠结合黄体酮治疗妊娠早期气血亏虚证先兆流产患者效果确切,能够快速改善症状,提高血清雌二醇和绒毛膜促性腺激素水平,提高保胎成功率的同时减少不良反应发生。
Objective To analyze the effect of Ejiaozhu combined with progesterone on threatened abortion patients with qi and blood deficiency syndrome in early pregnancy.Methods A total of 72 patients with threatened abortion in early preg-nancy who were admitted to Jiangxi Provincial Maternal and Child Health Care Hospital from July 2022 to December 2023 were selected as the research objects,all of whom met the diagnostic criteria of deficiency of qi and blood in traditional Chi-nese medicine.They were divided into a control group(36 cases)and an observation group(36 cases)according to random number table method.The control group was treated with single progesterone,and the observation group was treated with E-jiaozhu combined with progesterone.The symptom score,hormone level,success rate of fetal protection and incidence of ad-verse reactions of the two groups were compared.Results Before treatment,there was no statistically significant difference in the traditional Chinese medicine syndrome score and hormone levels between the two groups of patients(P>0.05).After treatment,the observation group had lower traditional Chinese medicine syndrome score,and higher serum estradiol(E_(2)),chorionic gonadotropin(HCG),and the success rate of fetal preservation than the control group,and the differences were sta-tistically significant(P<0.05).After treatment,there was no significant difference in the level of progesterone(P)between the two groups(P>0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group,with a statistically significant difference(P<0.05).Conclusion Ejiaozhu combined with progesterone has a definite effect on the treatment of threatened abortion patients with qi and blood deficiency syndrome in early pregnancy,which can quickly improve the symptoms,increase the levels of serum estradiol and chorionic gonadotropin,improve the success rate of fetal protection and reduce the incidence of adverse reactions.
作者
彭莉莎
邹阳
王茵
王慧民
田莉峰
黄琳玲
孙丽
PENG Lisha;ZOU Yang;WANG Yin;WANG Huimin;TIAN Lifeng;HUANG Linling;SUN Li(Department of Gynaecology,Jiangxi Provincial Maternal and Child Health Care Hospital,Jiangxi Province,Nanchang 330006,China)
出处
《中国当代医药》
CAS
2024年第30期23-26,31,共5页
China Modern Medicine
基金
江西省中医药管理局科技计划项目(2022B585)。
关键词
先兆流产
气血亏虚证
阿胶珠
黄体酮
妊娠早期
Threatened abortion
Qi and blood deficiency syndrome
Ejiaozhu
Progesterone
Early pregnancy
