摘要
目的分析对神经外科行机械通气的重症患者应用综合护理模式结合盐酸右美托咪定的临床应用效果。方法将2021年1月至2023年3月于南京医科大学附属无锡人民医院神经外科重症监护病房收治的84例行机械通气的重症患者作为研究对象,所有患者均采用盐酸右美托咪定进行镇静治疗,按照简单随机数字表法分为对照组及观察组。对照组42例患者采用常规干预,观察组42例患者在常规干预的基础上采用综合护理模式。比较2组患者的动脉血氧饱和度(SpO_(2))和平均动脉压(MAP)等。结果观察组的临床各指标(镇静起效时间、停药后苏醒时间等)和不良反应总发生率均优于对照组(P均<0.05);镇静后12 h、24 h和48 h,2组的SpO_(2)均高于同组镇静后1 h(P均<0.05),且观察组均高于同期对照组(P均<0.05);干预1周和2周后,2组的心率和MAP均低于同组干预前(P均<0.05),且观察组均低于同期对照组(P均<0.05)。结论综合护理模式结合盐酸右美托咪定可改善行机械通气重症患者的临床指标、SpO_(2)水平、心率和MAP,降低不良反应发生率。
Objective To analyze the clinical application effect of comprehensive nursing mode combined with dexmedetomidine hydrochloride in critically ill patients undergoing mechanical ventilation in neurosurgery.Methods Eighty-four critically ill patients with mechanical ventilation admitted to the Neurosurgery Intensive Care Unit of the Affiliated Wuxi People's Hospital of Nanjing Medical University from January 2021 to March 2023 were selected as the study subjects.All patients were treated with dexmedetomidine hydrochloride for sedation and divided into a control group and an observation group according to a simple random number table method.42 patients in the control group received routine intervention,while 42 patients in the observation group received comprehensive nursing mode on the basis of routine intervention.The arterial oxygen saturation(SpO_(2))level and mean arterial pressure(MAP)of the two groups were compared.Results The clinical indicators(sedative onset time,recovery time after discontinuation,etc.)and total incidence of adverse reactions in the observation group were better than those in the control group(all P<0.05).At 12 hours,24 hours,and 48 hours after sedation,the SpO_(2) levels in both groups were higher than those in the same group at 1 hour after sedation(all P<0.05),and were higher in the observation group than in the control group at the same time(all P<0.05).After 1 and 2 weeks of intervention,the heart rate and MAP of both groups were lower than before intervention in the same group(all P<0.05),and were lower in the observation group than in the control group at the same time(all P<0.05).Conclusion The comprehensive nursing mode combined with dexmedetomidine hydrochloride can improve the clinical indicators,SpO_(2) levels,heart rate,and MAP of critically ill patients undergoing mechanical ventilation,and reduce the incidence of adverse reactions.
作者
陈辛文
过云琳
尹庆
CHEN Xinwen;GUO Yunlin;YIN Qing(The Affiliated Wuxi People's Hospital of Nanjing Medical University,Wuxi,Jiangsu,214000,China)
出处
《中西医结合护理（中英文）》
2024年第9期21-24,共4页
Journal of Clinical Nursing in Practice
关键词
神经外科
机械通气
综合护理模式
盐酸右美托咪定
不良反应
neurosurgery
mechanical ventilation
comprehensive nursing mode
dexmedetomidine hydrochloride
adverse reaction
