摘要
昼夜节律紊乱与代谢疾病密切相关,其可通过直接影响肝脏或间接通过肝-脑轴、肠道菌群引起非酒精性脂肪性肝病(NAFLD)的发生。中医时间医学中阴阳、营卫、十二时辰及四时变化的节律与现代生物节律内涵相似。从中医时间医学角度出发,认为NAFLD的发病与阴阳消长日节律、营卫循行日节律、十二时辰节律以及四时节律的异常存在密切关系。通过分析NAFLD发生、发展相关的时间节律,加强了从中医时间医学角度对NAFLD发病的认识,为临床治疗提供新思路。
Circadian rhythm disorders are closely related to metabolic diseases,which can cause non-alcoholic fatty liver disease(NAFLD)by directly acting on the liver or indirectly affecting the liver through the liver-brain axis and intestinal flora.The rhythms of yin and yang,ying(营)and wei(卫),twelve hours and four seasons in traditional Chinese medicine(TCM)chronomedicine are similar to the connotations of modern biological rhythms.From the perspective of chronomedicine of TCM,the incidence of NAFLD is closely related to the abnormality of the daily rhythm of the waxing and waning of yin and yang,the daily rhythm of the circulation of ying and wei,the rhythm of twelve hours and four seasons.Through analyzing the rhythms related to the occurrence,development and prognosis of NAFLD,it is helpful to enhance the understanding of NAFLD in relation to time,so as to better guide the clinical diagnosis and treatment.
作者
郑攀攀
赵方
郑英伦
王秋雨
冯培民
ZHENG Panpan;ZHAO Fang;ZHENG Yinglun;WANG Qiuyu;FENG Peimin(Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Beijing,610072;Chengdu University of Traditional Chinese Medicine)
出处
《中医杂志》
CSCD
北大核心
2024年第19期2050-2055,共6页
Journal of Traditional Chinese Medicine
关键词
非酒精性脂肪性肝病
中医时间医学
昼夜节律
肝-脑轴
肠道菌群
non-alcoholic fatty liver disease
traditional Chinese medicine chronomedicine
circadian rhythm disorders
liver-brain axis
intestinal flora
