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调肝理脾法治疗痰瘀互结型肺部结节患者的效果评价

Evaluation of the Therapeutic Effect of Liver Regulating and Spleen Regulating Method on Patients with Pulmonary Nodules of Phlegm Stasis Type
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摘要 目的 分析痰瘀互结型肺部结节使用调肝理脾法治疗的临床功效。方法 目的抽样法选取2022年1—12月威海市中医院肿瘤科收治的70例痰瘀互结型患肺部结节患者为研究对象,按照治疗方法不同分为参比组和观察组,各35例。参比组使用左氧氟沙星进行对症治疗,观察组联合调和肝脾方治疗。对比两组肺结节相关指标、中医证候积分、不良反应和并发症发生情况。结果 治疗后,观察组结节直径、结节体积分别为(5.10±0.29)mm、(60.40±7.12)mm^(3),小于参比组的(6.32±0.57)mm、(97.55±10.28)mm^(3),差异有统计学意义(t=11.286、17.576,P均<0.05)。观察组各项中医证候积分低于参比组,差异有统计学意义(P均<0.05)。两组不良反应发生率对比,差异无统计学意义(P>0.05)。观察组并发症发病率为0,低于参比组的17.14%(6/35),差异有统计学意义(χ^(2)=4.557,P<0.05)。结论 使用调肝理脾法治疗痰瘀互结型肺部结节疗效显著,可缓解患者症状,药用安全性良好。 Objective To analyze the clinical efficacy of regulating the liver and regulating the spleen in treating pulmonary nodules with phlegm-stasis interjunction.Methods Seventy patients with pulmonary nodules of phlegm blood stasis type admitted to the Oncology Department of Weihai Traditional Chinese Medicine Hospital from January to December 2022 were selected as the research objects by target sampling method.They were divided into a reference group and an observation group according to different treatment methods,with thirty-five cases in each group.The reference group received symptomatic treatment with levofloxacin,while the observation group received combined treatment with reconciliation of liver and spleen.The incidence of pulmonary nodule related indicators,traditional Chinese medicine syndrome scores,adverse reactions,and complications were compared between two groups.Results After treatment,the diameter and volume of nodules in the observation group were(5.10±0.29) mm and(60.40±7.12) mm^(3),respectively,which were smaller than(6.32±0.57) mm and(97.55±10.28) mm^(3) in the reference group,the differences were statistically significant(t=11.286,17.576,both P<0.05).The scores of various traditional Chinese medicine syndromes in the observation group were lower than those in the reference group,and the differences were statistically significant(all P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).The incidence rate of complications in the observation group was 0,lower than 17.14%(6/35) in the reference group,the difference was statistically significant(χ^(2)=4.557,P<0.05).Conclusion The method of regulating the liver and regulating the spleen is effective in the treatment of pulmonary nodules with phlegm and blood stasis,which can alleviate patients' symptoms,and has good medical safety.
作者 刘艳霞 李雪妮 周扬 李雪健 张振宇 姜春状 LIU Yanxia;LI Xueni;ZHOU Yang;LI Xuejian;ZHANG Zhenyu;JIANG Chunzhuang(Department of Oncology,Weihai Traditional Chinese Medicine Hospital,Weihai 264200,Shandong,China)
出处 《系统医学》 2024年第16期5-8,共4页 Systems Medicine
基金 2022年度威海市中医药科技项目(2022111-13)。
关键词 调肝理脾法 痰瘀互结型 肺部结节 治疗效果 应用价值 临床评价 Liver regulating and spleen regulating method Phlegm and blood stasis accumulation type Pulmonary nodules Therapeutic effect Application value Clinical evaluation
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