摘要
目的:基于中医四诊客观化探讨泻南补北方干预绝经后动脉粥样硬化的临床效果。方法:选取绝经后动脉粥样硬化患者96例(疾病组),采用泻南补北方治疗,38名健康人设为对照组。采用《中医四诊信息采集表》、分光测色仪、TDA-1舌诊仪、DDMX-100型单道脉象仪,收集对照组脉象和疾病组的四诊数据,进行统计分析。使用社会网络分析软件UCINET分析疾病组治疗前后症状、舌象、脉象特征变化。结果:疾病组脉诊指标t1、h3、h3/h1、h4/h1、S、w显著高于对照组(P<0.05);h5、h5/h1显著低于对照组(P<0.05)。经泻南补北方治疗后,患者临床症状明显改善,患者面色的整体亮度和色度显著提升(P<0.05)。患者弦脉Ⅳ、虚弦脉象明显减少,弦Ⅱ、弦滑脉象明显增加。治疗后,脉诊指标t1、t5、w、w/t、h1、h5、h3/h1、h5/h1与治疗前和治疗初期(0周、1周)有明显差异,7周脉诊指标h5、h5/h1显著高于0周(P<0.05)。0—7周,红绛舌、白腻或黄腻苔明显减少,淡红舌、薄白苔明显增多;6周和7周舌象参数指标L、I值显著高于0周(P<0.05)。结论:泻南补北方可以改善绝经后动脉粥样硬化患者的面色、舌象、脉象及临床症状,中医四诊客观化指标可以为中医临床病情演变及临床疗效评价提供有效依据。
Objective:To explore the clinical effect of reducing the south and reinforcing the north(RSRN)method on postmenopausal atherosclerosis based on modern traditional Chinese medicine(TCM)four diagnostic objective information.Methods:According to the inclusion criteria,96 patients with postmenopausal atherosclerosis(disease group)(treated by RSRN)and 38 healthy people(control group)were selected.The pulse conditions of control group were obtained.And the four diagnostic information of patients was collected by using the information collection form of four diagnosis of TCM,spectrophotometer CM-2600,TDA-1 small tongue image instrument,DDMX-100 single channel instrument.The information was then statistical analyzed.Social network analysis software UCINET was used to analyze the changes of patients'symptoms,tongue,and pulse characteristics before and after RSRN treatment.Results:The pulse indexes tl,h3,h3/h1,h4/h1,S,w in the disease group were significantly higher than those in the control group;h5,h5/h1 were significantly lower than those in the control group(P<0.05).After the treatment of RSRN,the clinical symptom information of patients was reduced.The facial color indexes and the overall brightness and chroma of the patient's facial color were significantly improved.The string IV and virtual string pulse significantly decreased,while string II and wiry slippery pulse increased.The pulse parameters of tl,t5,w,w/t,h,h5,h3/h1,h5/h1 at week 7 were different from those at week 0,1,h5,h5/h1 at week 7 were higher than those at week 0(P<0.05).From 0 to 7 week,bright red tongue,white or yellow greasy coating of patients'tongue image were decreased,light red tongue with thin white coating were increased.The L value of tongue image at week 6 and 7 was higher than that at O and 1 week(P<0.05).Conclusion:The RSRN method can improve the complexion,tongue,pulse,and clinical symptoms of postmenopausal atherosclerosis patients.Objective indicators of the four diagnostic methods of TCM can be used to evaluate the clinical treatment ef
作者
吴宏进
戴薇薇
李深广
屠立平
许家佗
张志枫
WU Hongjin;DAI Weiwei;LI Shenguang;TU Liping;XU Jiatuo;ZHANG Zhifeng(Longhua Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China;Shanghai Minhang Integrated Traditional Chinese and Western Medicine Hospital,Shanghai 201199,China;Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China)
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2024年第9期5076-5082,共7页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
上海市闵行区中医特色品牌专科建设项目(No.ZYPP-03)
上海市闵行区名老中医工作室建设项目(No.mhmlzy01)。
关键词
泻南补北法
绝经后动脉粥样硬化
四诊信息
客观化
中药复方
疗效评价
Reducing the south and reinforcing the north method
Postmenopausal atherosclerosis
Four diagnostic information
Objectification
Traditional Chinese medicine compound
Therapeutic effective evaluation
