摘要
溶血尿毒综合征是引起儿童急性肾衰竭的常见病因之一,主要临床表现是急性肾损伤、血小板减少及急性微血管病性溶血性贫血(外周血涂片可找到红细胞碎片)。溶血尿毒综合征早期起病急,临床呈进行性、破坏性进展,病情凶险,病死率高,属于儿童危重症,后期则以慢性肾脏损害为主。因此,对该病早期识别并积极干预治疗对保护肾脏功能、阻止或延缓肾脏疾病进展及其重要。本文就溶血尿毒综合征的诊疗进展进行综述,以期在临床工作中对该病早期识别,积极干预,改善预后。
Hemolytic uremic syndrome is one of the common causes of acute renal failure in children,and the main clinical manifestations are acute kidney injury,thrombocytopenia and acute microangiopathic hemolytic anemia(red blood cell fragments can be found on peripheral blood smear).Hemolytic uremic syndrome has a rapid onset in the early stage,progressive and destructive clinical progression,and is a critical illness in children with a high mortality rate,while chronic renal damage is the main disease in the later stage.Therefore,early recognition of the disease and active intervention in treatment are important to protect kidney function and prevent or delay the progression of kidney disease.This article reviews the progress of diagnosis and treatment of hemolytic uremic syndrome,in order to identify the disease early,actively intervene and improve the prognosis in clinical work.
作者
李丹丹
LI Dandan(Department of Pediatrics,the Fifth People's Hospital of Longgang District,Shenzhen 518111,China)
出处
《中国医药指南》
2024年第27期66-70,共5页
Guide of China Medicine
关键词
溶血尿毒综合征
儿童
肾衰竭
诊断
治疗
Hemolytic-uremic syndrome
Children
Renal failure
Diagnosis
Treatment
