摘要
目的:通过回顾性分析研究不同时间点相关指标动态变化趋势,观察穴位贴敷治疗慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)在时间因素方面的疗效持续性。方法:选取符合标准的连续3年进行三伏天穴位贴敷的30例稳定期COPD患者为研究对象。每年均以末伏贴敷结束8月26日为观察节点,分别进行肺功能检测、COPD评估测试(COPD Assessment Test,CAT)、6分钟步行测定(6WMT)、急性加重次数(N)、呼吸困难量表(mMRC)的记录,同时采用单因素重复测量设计方差进行统计分析。结果:被试内因素(时间)对FVC、FEV1、CAT积分、6WMT、N的主效应均具有统计学意义(P<0.05);被试内因素(时间)对FEV_(1)/FVC(%)、mMRC积分的主效应不具有统计学意义(P>0.05)。通过对3个节点之间成对比较显示:节点2与节点1比较,FVC、FEV_(1)差异具有统计学意义(P<0.05);FEV1/FVC(%)、CAT积分、6WMT、N、mMRC积分差异无统计学意义(P>0.05)。节点2与节点3比较,CAT积分、N差异具有统计学意义(P<0.05);FVC、FEV_(1)、FEV1/FVC(%)、6WMT、mMRC积分差异无统计学意义(P>0.05)。节点3与节点1比较,FVC、FEV_(1)、CAT积分、6WMT、N差异具有统计学意义(P<0.05);FEV1/FVC(%)、mMRC积分差异无统计学意义(P>0.05)。结论:穴位贴敷可持续性改变FVC、FEV1、CAT积分、6WMT、N,对于FEV1/FVC(%)、mMRC积分无明显影响,因此连续三年穴位贴敷治疗COPD具有可持续性。
Objective:To observe the duration of the efficacy of acupoint application in the treatment of chronic obstructive pulmonary disease(COPD)in terms of time factors by retrospectively analyzing the dynamic trend of related indicators at different time points.Methods:Thirty patients with stable COPD who met the criteria and received acupoint application during the three-day period for three consecutive years were selected as the research subjects.August 26,the end of the last day of the dog days,was used as the observation node every year.Pulmonary function tests,COPD Assessment Test(CAT),6-minute walk measurement(6WMT),number of acute exacerbations(N),and dyspnea scale(mMRC)were recorded,and single-factor repeated measures design variance was used for statistical analysis.Results:The main effects of the within-subject factor(time)on FVC,FEV1,CAT score,6WMT,and N were statistically significant(P<0.05);the main effects of the within-subject factor(time)on FEV1/FVC(%)and mMRC score were not statistically significant(P>0.05).Paired comparisons among the three nodes showed that:there were statistically significant differences in FVC and FEV1 between node 2 and node 1(P<0.05);there were no statistically significant differences in FEV1/FVC(%),CAT score,6WMT,N,and mMRC score(P>0.05).There were statistically significant differences in CAT score and N between node 2 and node 3(P<0.05);there were no statistically significant differences in FVC,FEV1,FEV1/FVC(%),6WMT,and mMRC score(P>0.05).There were statistically significant differences in FVC,FEV1,CAT score,6WMT,and N between node 3 and node 1(P<0.05);there were no statistically significant differences in FEV1/FVC(%)and mMRC score(P>0.05).Conclusion:Acupoint sticking can sustainably change FVC,FEV1,CAT score,6WMT,and N,but has no significant effect on FEV1/FVC(%)and mMRC score.Therefore,acupoint sticking for three consecutive years is sustainable in the treatment of COPD.
作者
牛文敏
黄平富
王浩
NIU Wenmin;HUANG Pingfu;WANG Hao(Chuzhou Hospital of Integrated Traditional Chinese and Western Medicine,Anhui University of Chinese Medicine,Anhui Chuzhou 239000,China)
出处
《中医药临床杂志》
2024年第9期1757-1762,共6页
Clinical Journal of Traditional Chinese Medicine
基金
国家自然科学基金区域创新联合基金项目(U20A20398)
安徽省中医药传承创新科研项目(2022CCYB09)
安徽省“十四五”中医优势专科建设项目(皖中医药服务秘〔2021〕71号)
滁州市2021年临床重点专科建设项目(滁卫科秘〔2021〕261号)。
关键词
穴位贴敷
慢性阻塞性肺疾病
时间
肺功能
问卷
Acupoint sticking
Chronic obstructive pulmonary disease
Time
Lung function
Questionnaire
