摘要
拟诺卡菌是一种罕见的机会性致病菌,随着器官移植、肿瘤患者增多及临床诊疗水平和实验室技术的提高,有关拟诺卡菌感染的文献报道日益增多,但由达松威尔拟诺卡菌引起的肺部感染文献报道较少见。肺癌合并达松威尔拟诺卡菌肺部感染更是较为罕见,因其临床表现和影像学无特异性,细菌培养难度大,容易漏诊、误诊,且患者预后较差。大理大学第一附属医院收治1例肺癌合并达松威尔拟诺卡菌肺部感染患者,通过化疗联合磺胺甲恶唑/甲氧苄啶、莫西沙星抗感染治疗后病情好转,复习既往相关文献,以期提高临床医生对该病的认识。
Nocardia is a rare opportunistic pathogen.The number of reported cases of infections caused by this bacterium is increasing,associated with the rising prevalence of organ transplantation,cancer,as well as improvements in clinical diagnostics and laboratory techniques.However,pulmonary infections caused by Nocardia Darsonwierii are rarely reported.Lung cancer combined with Nocardia Darsonwierii pulmonary infection is even more uncommon.Due to its nonspecific clinical manifestations and imaging features,and the difficulty in culturing the bacterium,such infections are prone to being overlooked or misdiagnosed,and the prognosis for affected patients is often poor.The First Affiliated Hospital of Dali University treated a patient with lung cancer and a concurrent Nocardia Darsonwierii pulmonary infection.The patient′s condition improved following chemotherapy combined with antimicrobial treatment using sulfamethoxazole/trimethoprim and moxifloxacin.A review of relevant literature was conducted to enhance clinical awareness of this condition.
作者
和倩
管勤朝
朱高沣
徐文浩
沈文娟
周刊
张丽
李智
管风云
顾伟
HE Qian;GUAN Qinzhao;ZHU Gaofeng;XU Wenghao;SHEN Wenjuan;ZHOU Kan;ZHANG Li;LI Zhi;GUAN Fengyun;GU Wei(Clinical Medicine Branch of Infectious Diseases of Yunnan Province/Key Laboratory of Infectious Diseases of Education Department of Yunnan Province/Department of Infectious Diseases,the First Affiliated Hospital of Dali University,Dali,Yunnan 671000,China;Department of Critical Care Medicine,Xiaogan Hospital Affiliated to Wuhan University of Science and Technology,Xiaogan,Hubei 432000,China;Department of Pediatrics,the First Affiliated Hospital of Dali University,Dali,Yunnan 671000,China;Department of Radiology,the First People′s Hospital of Xiaogan,Xiaogan,Hubei 432000,China)
出处
《现代医药卫生》
2024年第17期2942-2944,2947,共4页
Journal of Modern Medicine & Health
