摘要
目的分析β2-微球蛋白(β2-microglobulin,β2-MG)与血肌酐/血红蛋白比值联合检验诊断糖尿病早期肾损伤的价值。方法选取2022年7月—2024年1月泰兴市中医院收治的82例糖尿病患者为研究对象,其中60例为单纯糖尿病患者,22例为糖尿病早期肾损伤患者,所有患者进行β2-MG、血肌酐/血红蛋白比值检测,对比不同检查方法的诊断价值(准确度、灵敏度、特异度)。结果β2-MG联合血肌酐/血红蛋白比值检测的灵敏度、准确度高于β2-MG、血肌酐/血红蛋白比值单独检测,差异有统计学意义(P均<0.05)。β2-MG与血肌酐/血红蛋白比值检测的灵敏度、特异度、准确度对比,差异无统计学意义(P均>0.05)。结论β2-MG与血肌酐/血红蛋白比值联合检验诊断糖尿病早期肾损伤的灵敏度、准确度均高于单一β2-MG、血肌酐/血红蛋白比值检测。
Objective To analyze the value of combined test ofβ2-microglobulin(β2-MG)and serum creatinine/he⁃moglobin ratio in the diagnosis of early renal injury in diabetes mellitus.Methods A total of 82 diabetic patients ad⁃mitted to Taixing Hospital of Traditional Chinese Medicine from July 2022 to January 2024 were selected as the re⁃search objects,including 60 patients with simple diabetes mellitus and 22 patients with early renal injury in diabetes mellitus.All patients were tested forβ2-MG and serum creatinine/hemoglobin ratio,and the diagnostic values(accu⁃racy,sensitivity and specificity)of different examination methods were compared.Results The sensitivity and accu⁃racy ofβ2-MG combined with serum creatinine/hemoglobin ratio were higher than those ofβ2-MG and serum cre⁃atinine/hemoglobin ratio,and the differences were statistically significant(all P<0.05).There were no significant dif⁃ference in sensitivity,specificity and accuracy betweenβ2-MG and serum creatinine/hemoglobin ratio(all P>0.05).Conclusion The sensitivity and accuracy of combined detection ofβ2-MG and serum creatinine/hemoglobin ratio in the diagnosis of early renal injury in diabetes mellitus were higher than those of singleβ2-MG and serum creatinine/hemoglobin ratio.
作者
张鹏
程贝
朱宇
王翔
ZHANG Peng;CHENG Bei;ZHU Yu;WANG Xiang(Department of Laboratory,Taixing Hospital of Traditional Chinese Medicine,Taixing 225400,Jiangsu,China)
出处
《糖尿病新世界》
2024年第12期50-52,共3页
Diabetes New World
