摘要
目的探究糖尿病早期肾损伤患者尿微量白蛋白(mAlb)及尿常规变化的临床意义。方法纳入本院2022年1月~12月就诊的糖尿病早期肾损伤患者64例(研究组)及同时期健康体检者50例(对照组)作为研究对象。两组均行mAlb及尿常规检查,比较检查结果及阳性检出率,并分析mAlb及尿常规诊断价值。结果研究组mAlb、尿白细胞比对照组高,pH比对照组低(P<0.05);研究组尿糖及尿蛋白阴性率分别为43.75%、73.44%,均比对照组的96.00%、98.00%低(P<0.05);两组尿比重相比无差异(P>0.05)。研究组mAlb及尿常规阳性检出率分别为87.50%、84.38%,均比对照组的2.00%、8.00%高(P<0.05)。mAlb、尿常规联合检查诊断糖尿病早期肾损伤的准确率为98.44%,比mAlb、尿常规单一检查的87.50%、84.38%高(P<0.05)。结论糖尿病早期肾损伤患者mAlb及尿常规均处于动态变化过程,临床中动态监测其水平变化有助于及时诊断糖尿病早期肾损伤,临床价值较高。
Objective To investigate the clinical significance of urinary microalbumin(mAlb)and routine changes in patients with early renal injury in diabetes mellitus.Methods The study group was from our hospital with 64 early diabetic kidney injury patients from January to December 2022,and the control group with 50 healthy subjects during the same time in our hospital..mAlb and urine routine examination were performed in both groups.The results and positive detection rate were compared,and the accuracy of single and combined mAlb and urine routine in the diagnosis of early diabetic kidney injury was analyzed.Results compared with control group,mAlb and urine white blood cells were higher,but pH was lower(P<0.05).The negative rates of urine sugar and urine protein in the study group were 43.75%and 73.44%,which were lower than 96.00%and 98.00%in the control group(P<0.05).There was no difference in urinary specific gravity between the two groups(P>0.05).The positive rates of mAlb and urine routine in the study group were 87.50%and 84.38%,and the control group(2.00%and 8.00%,P<0.05).The accuracy of mAlb and urine routine examination in the diagnosis of early diabetic kidney injury was 98.44%,and they were higher than routine examination in 87.50%and 84.38%(P<0.05).Conclusion mAlb and urine routine in patients with early diabetic kidney injury are in the process of dynamic change.Dynamic monitoring of the changes in the level of early diabetic kidney injury is helpful for timely diagnosis,and provides reference for the selection of follow-up treatment and disease evaluation of patients,which is of high clinical value.
作者
王霖婧
聂晓斌
赵裴
WANG Lin-jing;NIE Xiao-bin;ZHAO Pei(Zhengzhou Ninth People's Hospital,Zhengzhou 450000,Henan Province,China)
出处
《罕少疾病杂志》
2024年第8期83-85,共3页
Journal of Rare and Uncommon Diseases
关键词
糖尿病肾病
早期肾损伤
尿微量白蛋白
尿常规
Diabetic Nephropathy
Early Renal Injury
Urinary Microalbumin
Urine Routine
