摘要
通过多元醇还原法制备了大长径比的银(Ag)纳米线微纳结构,并将其作为表面增强拉曼散射(SERS)的基底,以罗丹明6G(R6G)为探针分子研究了Ag纳米线的SERS效应,实验结果表明,Ag纳米线SERS基底对R6G的最低检测浓度为10^(-10)mol/L,增强因子约为1.0×10^(4);以610和772 cm^(-1)散射峰强度计算得出的相对标准偏差(RSD)分别为14.66%和13.75%,表明R6G在Ag纳米线基底上的SERS信号强度分布较均一,具有较好的信号重现性.另外,将Ag纳米线作为SERS基底用于检测尿液中低含量的D-(+)-葡萄糖,发现Ag纳米线对D-(+)-葡萄糖的浓度检出限低至10^(-6)mg/mL,RSD值低于8%,说明Ag纳米线对于D-(+)-葡萄糖的痕量检测具有良好的灵敏度和信号重现性.该研究可为糖尿病的血糖监测和早期预防提供一定的技术支持.
The silver(Ag)snowiness micro-nanostructures with a large aspect ratio was prepared by the polyol reduc⁃tion method,and it was used as the substrate for surface enhanced Raman scattering(SERS).Rhodamine 6G(R6G)was used as the probe molecule to study the SERS effect of Ag nanowires.The results showed that the minimum detection concentration of R6G on Ag nanowires was 10^(-10)mol/L,and the enhancement factor(EF)was about 1.0×10^(4).The relative standard deviation(RSD)calculated based on the scattering peak intensities of 610 and 772 cm^(-1)was 14.66%and 13.75%,respectively,indicating that the SERS signal intensity distribution of R6G on Ag nanowires substrate was relatively uniform to lead to good signal reproducibility.In addition,Ag nanowires were used as SERS substrates to detect low levels of D-(+)-glucose in urine.It was found that the detection limit of Ag nanowires for D-(+)-glucose concentration was as low as 10^(-6)mg/mL,and the RSD value was less than 8%,indicating that Ag nanowires had good sensitivity and signal reproducibility for trace detection of D-(+)-glucose.This study could provide some technical support for blood glucose monitoring and early prevention of diabetes.
作者
张禹
陈龙
王中才
胡广
徐东
盛全康
陈奥
陈韶云
胡成龙
陈建
ZHANG Yu;CHEN Long;WANG Zhongcai;HU Guang;XU Dong;SHENG Quankang;CHEN Ao;CHEN Shaoyun;HU Chenglong;CHEN Jian(School of Optoelectronic Materials&Technology,Jianghan University,Wuhan 430056,China;Shenzhen Purcotton Technology Co.,Ltd.,Shenzhen 518110,China;Instrumental Analysis and Research Center,Sun Yat-sen University,Guangzhou 510275,China)
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
2024年第9期46-54,共9页
Chemical Journal of Chinese Universities
基金
湖北省自然科学基金(批准号:2023AFB890)资助.
关键词
表面增强拉曼光谱
银纳米线
糖尿病
葡萄糖
痕量检测
Surface-enhanced Raman spectroscopy
Silver nanowires
Diabetes
Glucose
Trace detection
