摘要
目的:探讨临床药师干预对提高依达拉奉右莰醇注射用浓溶液在脑卒中患者中使用合理性的作用及对疾病诊断相关分组(DRG)付费的影响。方法:回顾性分析2022年9月至2023年6月于广元市中心医院接受治疗并使用依达拉奉右莰醇注射用浓溶液的脑卒中患者相关信息,纳入临床药师干预前(2022年9月1日至2023年2月24日)147例患者、干预后(2023年2月25日至6月30日)149例患者,比较干预前后患者不合理医嘱发生率和不良反应发生情况,以及平均住院时间、药品费用、住院费用和DRG付费后的盈亏。结果:干预后,不合理医嘱发生率为19.46%(29/149),低于干预前的80.95%(119/147)。干预后,有1例患者发生不良反应,低于干预前的5例。干预后,患者的平均住院时间为10.56 d,短于干预前的12.60 d;患者的平均药品费用、平均住院费用和DRG付费后的盈亏分别为7 300.07元、28 592.75元和亏3 347.83元,低于干预前的9 437.71元、34 740.39元和亏4 408.02元,上述差异均有统计学意义(P<0.05)。结论:临床药师干预脑卒中患者使用依达拉奉右莰醇注射用浓溶液具有很高的积极作用,可减少不合理医嘱和不良反应的发生,在一定程度上减轻患者的经济负担,在DRG付费模式下对医院的成本控制起到积极作用。
OBJECTIVE:To probe into the role of clinical pharmacists’intervention in improving the application rationality of edaravone and dexborneol concentrated solution for injection in patients with stroke and its effects on diagnosis-related groups(DRG)payment.METHODS:Related information of patients with stroke who received treatment and were given edaravone and dexborneol concentrated solution for injection in Guangyuan Central Hospital from Sept.2022 to Jun.2023 were retrospectively analyzed,147 patients before intervention(from Sept.1st,2022 to Feb.24th,2023)and 149 patients after intervention(from Feb.25th to Jun.30th,2023)by clinical pharmacists were enrolled to compare the incidences of irrational medical orders and adverse drug reactions before and after the intervention,as well as the average length of stay,drug costs,hospitalization costs and profit/loss after DRG payment.RESULTS:After intervention,the incidence of irrational medical orders was 19.46%(29/149),lower than that before intervention(80.95%,119/147).After intervention,1 patient had adverse drug reactions,less than 5 patients before intervention.After intervention,the average length of stay was 10.56 d,shorter than 12.60 d of before intervention.The average drug cost,average hospitalization cost and profit/loss after DRG payment were 7300.07 RMB,28592.75 RMB and 3347.83 RMB loss,respectively,which were lower than 9437.71 RMB,34740.39 RMB and 4408.02 RMB loss before intervention,the differences were statistically significant(P<0.05).CONCLUSIONS:Clinical pharmacists’intervention on the application of edaravone and dexborneol concentrated solution for injection in patients with stoke has higher positive effect,which can reduce the occurrence of irrational medical orders and adverse drug reactions,relieve the economic burden of patients to a certain extent,and play a positive role in cost control of hospitals under the DRG payment model.
作者
赵洋
马泉吉
吴建章
杨雪琴
黄丽丽
李秋俞
王靖淞
ZHAO Yang;MA Quanji;WU Jianzhang;YANG Xueqin;HUANG Lili;LI Qiuyu;WANGJingsong(Dept.of Pharmacy,Guangyuan Central Hospital,Sichuan Guangyuan 628000,China;The Eye Hospital,School of Ophthalmology&Optometry,Wenzhou Medical University,Zhejiang Wenzhou 325027,China;Oujiang Laboratory(Zhejiang Lab for Regenerative Medicine,Vision and Brain Health),Zhejiang Wenzhou 325700,China;Dept.of Pharmacy,Ningbo Medical Center Lihuili Hospital,Zhejiang Ningbo 315000,China)
出处
《中国医院用药评价与分析》
2024年第8期1007-1009,1015,共4页
Evaluation and Analysis of Drug-use in Hospitals of China
基金
国家自然科学基金资助项目(No.82003755)。
