摘要
近年来,随着人们饮食结构等因素的变化,消化道肿瘤的患病率不断增加,其中胃癌是较为常见的消化系统恶性肿瘤之一。而我国电子内镜的迅速发展,对于早期胃癌(early gastric cancer, EGC)的诊断提供了巨大帮助。因此,准确地探讨EGC浸润深度的影响因素,对于选择治疗方式和判断患者预后具有很大意义。我们通过阅读大量文献,对于影响EGC浸润深度的因素进行归纳总结,我们发现EGC浸润深度可能受多种因素的影响,包括患者的年龄与性别、肿瘤位置、病理类型、大小和数目、病变特征及H.pylori感染等。但总结后发现,性别和年龄对于EGC浸润深度的影响差异无统计学意义,肿瘤位置是否对浸润深度有影响尚存在争议,肠型胃癌、组织学类型、肿瘤直径≥2 cm、溃疡型、H.pylori感染均影响EGC的浸润深度。因此,本文旨在综述EGC浸润深度的影响因素,以期对于EGC的诊断与治疗提供帮助。
In recent years,with the changes of people′s dietary structure and other factors,the prevalence of gastrointestinal tumors has been increasing.Among them,gastric cnacer is one of the most common malignant tumors of the digestive system.The rapid development of electronic gastroscopy in our country has provided great help for the diagnosis of early gastric cancer(EGC).Therefore,it is of great significance to accurately discuss the influencing factors of the infiltration depth of EGC for selection of treatment methods and judgment patients′prognosis.Through reading a large number of literatures,we have summarized the factors affecting the depth of invasion of EGC.We found that the depth of invasion of EGC may be affected by a variety of factors,including age and gender of patients,tumor location,pathological type,size and number of tumors,lesion characteristics,and H.pylori infection.However,it was found that gender and age had no statistically significant effect on the depth of invasion of EGC,and whether the location of tumor had an effect on the depth of invasion was still controversial.Intestinal gastric cancer,histological type,tumor diameter≥2 cm,ulcerative type,and H.pylori infection all affected the depth of invasion of EGC.Therefore,this article aimed to review the influencing factors of invasion depth of EGC,in order to provide help for the diagnosis and treatment of EGC.
作者
刘晓娜
武希润
LIU Xiaona;WU Xirun(Shanxi Medical University,Taiyuan 030001;Department of Gastroenterology,the Second Hospital of Shanxi Medical University,China)
出处
《胃肠病学和肝病学杂志》
CAS
2024年第8期1055-1058,1063,共5页
Chinese Journal of Gastroenterology and Hepatology
关键词
早期胃癌
浸润深度
影响因素
Early gastric cancer
Invasion depth
Influencing factors