摘要
外阴白斑是妇科常见病,临床上可以通过患者症状、体征对该病作出临床诊断,但外阴活组织病理检查(外阴活检)是诊断的金标准,也是疗效评价的客观指标。鉴于外阴活检的有创性和女性外阴的特殊性,无论是基于诊断目的的初次活检还是基于疗效评估目的的再次活检在临床应用的阻力都非常大,同时有违人道精神和微无创的医学发展理念。有鉴于此,团队结合近三十年使用自制中药膏无创治疗该病的经历、经验,率先提出使用皮肤镜对该病进行无创诊断和疗效评估的理念并进行了系列开创性研究,取得相应研究结果。本文即根据外阴白斑研究现状和团队的研究结果撰写的一篇述评,希望借此引起妇产科学界对皮肤镜用于外阴白斑无创诊断与疗效评估的重视,逐渐提高其研究、应用的普及率、准确性,服务临床、造福患者。
Vulvar leukoplakia is a common gynecological disease,which could be clinically diagnosed based on the patient’s symptoms and signs.However,pathological examination of the external genitalia(vulvar biopsy)is the gold standard for diagnosis and also the objective indicator for evaluating its therapeutic effects.Due to the invasive nature of vulvar biopsy and the particularity of the female external genitalia,both the initial biopsy based on diagnostic purposes and re-biopsy based on efficacy evaluation have significant resistance in clinical application,which goes against the humanitarian spirit and the concept of minimally invasive medical development.In view of this,the team,based on nearly 30 years of experience in non-invasive treatment of this disease by using self-made traditional Chinese medicine ointment,took the lead in proposing the concept of using dermatoscopy for non-invasive diagnosis and efficacy evaluation of this disease,and conducted a series of pioneering studies,achieving corresponding research results.This article was a review written based on the current research status of vulvar leukoplakia and the research results of the team.It is hoped that this review will raise the attention of the obstetrics and gynecology community to the use of dermatoscopy for non-invasive diagnosis and efficacy evaluation of vulvar leukoplakia,and gradually improve the popularity and accuracy of its research and application,and serves clinical practice and benefit the patients finally.
作者
肖雁冰
苏远华
Xiao Yanbing;Su Yuanhua(Gynecology Department of Zunyi Maternal and Child Health Hospital,Zunyi Guizhou 563000,China;Gynecology Department of Guizhou Aerospace Hospital,Zunyi Guizhou 563000,China)
出处
《遵义医科大学学报》
2024年第8期741-748,共8页
Journal of Zunyi Medical University
关键词
外阴白斑
皮肤镜
无创
诊断
疗效评估
vulvar leukoplakia
dermatoscope
non invasive
diagnosis
efficacy evaluation
