摘要
目的:观察艾司氯胺酮联合舒芬太尼镇痛在剖宫产术后患者中的应用效果。方法:选取2022年3月至2023年7月该院收治的94例剖宫产手术患者进行前瞻性研究。按随机数字表法将其分为对照组与观察组各47例。术后对照组给予舒芬太尼静脉自控镇痛(PCIA),观察组在对照组基础上联合盐酸艾司氯胺酮注射液PCIA。比较两组术后疼痛程度[视觉模拟评分法(VAS)]评分,术后24、48 h镇痛泵按压次数和不良反应发生率。结果:术后12、24、48 h,观察组VAS评分均低于对照组,差异有统计学意义(P<0.05);观察组术后24、48 h镇痛泵按压次数均少于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:艾司氯胺酮联合舒芬太尼镇痛应用于剖宫产手术患者可降低疼痛程度评分,减少镇痛泵按压次数,其效果优于单纯舒芬太尼镇痛。
Objective:To observe application effects of Esketamine combined with Sufentanil analgesia in patients after cesarean section.Methods:A prospective study was conducted on 94 patients with cesarean section admitted to the hospital from March 2022 to July 2023.According to the random number table method,they were divided into control group and observation group,47 cases in each group.After the surgery,the control group was given Sufentanil patient-controlled intravenous analgesia(PCIA),while the observation group was combined with Esketamine hydrochloride injection PCIA on the basis of that of the control group.The postoperative pain degree[visual analogue scale(VAS)]score,the number of analgesic pump pressing times 24 and 48 h after the surgery,and the incidence of adverse reactions were compared between the two groups.Results:At 12,24 and 48 h after the surgery,the VAS scores of the observation group were lower than those of the control group,and the differences were statistically significant(P<0.05).The number of analgesic pump pressing times in the observation group was less than that in the control group at 24 and 48 h after the surgery,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Esketamine combined with Sufentanil analgesia in the patients after cesarean section can reduce the pain scores and the number of analgesic pump pressing times.Moreover,it is superior to simple Sufentanil analgesia.
作者
田艳梅
TIAN Yanmei(Department of Anesthesiology of Xinxiang Maternal and Child Health Hospital,Xinxiang 453000 Henan,China)
出处
《中国民康医学》
2024年第16期61-63,共3页
Medical Journal of Chinese People’s Health
