摘要
目的:利用名医传承平台,探讨“国医大师”张震教授治疗不寐的处方用药规律及经验。方法:将2009年1月1日至2011年12月31日间田春洪教授随诊张震教授,记录的112份不寐病例,将症状、处方用药等录入“名医传承平台”,进行审核和核对;对核心及辅助药物、两味中药间关联度、中药与症状的关联度进行数据挖掘与分析;结合张震教授临证经验,对数据挖掘结果进行分析。结果:数据分析得出核心药物共31味,前五位依次为甘草、钩藤、薄荷、夜合花、茯神;两药关联度得出8515个组合,前五位依次为首乌藤与酸枣仁、延胡索与香附、砂仁与木香、酸枣仁与钩藤、酸枣仁与茯神;原始处方中伴随症状频率>10%的症状依次为心悸、头昏、乏力、神倦、耳鸣、头晕、头痛,对应药物分别为麦冬、葛根、香附、延胡索、葛根、防风、延胡索等。结论:张震教授治疗不寐的药物以疏肝解郁、疏调气机安神为主,用药特点为药法自然、选用“隐药”,荣养心阴、助神守舍,气机条畅、夜眠安然等,常以药对增强方药治疗失眠的效果。
Objective:To discuss national master of TCM and professor Zhang Zhen′s medication laws and experience in treating insomnia using auxiliary platform for famous doctors.Methods:The symptoms,the prescriptions and the medications of 112 cases of insomnia which were recorded by professor Tian Chunhong between January 1,2009 and December 31,2011,were entered into"auxiliary platform for famous doctors",examined and checked;data mining and analysis of the associations between the core drugs and auxiliary drugs,between two drugs,the medicine and symptoms were carried out,and the results were analyzed in combination with Professor Zhang Zhen′s clinical experience.Results:The data analysis has yielded 31 core herbs,and the top five ones were Gancao(glycyrrhizae radix et rhizoma),Gouteng(Uncariae ramulus cum uncis),Bohe(Menthae haplocalycis herba),Yehehua(Albiziae flos)and Fushen[Poria cocos(Schw)wolf.];Two-drug correlations yielded 8515 combinations,and the top five combinations were Shouwuteng(Polygoni multiflori caulis)and Suanzaoren(Ziziphi spinosae semen),Yanhusuo(Corydalis rhizoma)and Xiangfu(Cyperi rhizoma),Sharen(Amomi fructus)and Muxiang(Aucklandiae radix),Suanzaoren and Gouteng,Suanzaoren and Fushen;The concomitant symptoms with the frequency greater than 10%from the original prescriptions were palpitation,dizziness,weakness,weariness,tinnitus,vertigo and headache,the corresponding herbs were Maidong,Gegen,Xiangfu,Yanhusuo,Gegen,Fangfeng and Yanhusuo respectively.Conclusion:The drugs used in the treatment of insomnia by Profressor Zhang Zhen could disperse stagnated liver Qi and relieve Qi stagnation,adjust Qi movement and tranquilise the mind mainly,and the medication is characterized by natural pharmaceutical law,and selection of"hidden medicine",which could nourish heart Yin,and tranquilise the mind,in order to ensure the patients'smooth Qi movement and sound sleep,and he often applies the drug combinations to improve clinical effects for insomnia.
作者
朱建平
田原
鲁欣羽
田春洪
张震(指导)
ZHU Jianping;TIAN Yuan;LU Xinyu;TIAN Chunhong;ZHANG Zhen(First Clinical Medical College,Yunnan University of Chinese Medicine,Kunming 650200,China;Yunnan Institute of Traditional Chinese Medicine,Kunming 650000,China)
出处
《西部中医药》
2024年第8期24-28,共5页
Western Journal of Traditional Chinese Medicine
基金
国家重点研发计划项目(2018YFC1704104)。
