摘要
目的探讨急性缺血性脑卒中(AIS)患者发生认知功能障碍(CI)的相关影响因素及干预措施.方法回顾性分析九江市第一人民医院2021年6月-2023年10月收治的104例AIS患者临床资料,均于入院7d后采用蒙特利尔认知评估量表(MoCA)评估认知功能,依据MoCA评分将AIS患者分为CI组及无CI组,分别收集两组年龄、性别、文化程度、婚姻状况、吸烟史、饮酒史、合并高脂血症、合并糖尿病、合并高血压、美国国立卫生研究卒中量表(NIHSS)评分、脑梗死位置、高尿酸血症等多方面基础资料,先行单因素分析,待获得有统计学差异的项目后再行Logistic回归分析,最终获得影响AIS患者发生CI的高危因素.结果104例患者共出现37例CI,发生率35.58%(37/104);两组年龄、吸烟史、合并糖尿病、NIHSS评分、脑梗死位置、合并高尿酸血症相比,差异有统计学意义(P<0.05);多因素显示,年龄≥70岁(OR=2.571,95%置信区间=1.120-5.905)、有吸烟史(OR=3.861,95%置信区间=1.657-8.994)、合并糖尿病(OR=2.481,95%置信区间=1.081-5.690)、NIHSS评分≥15分(OR=3.986,95%置信区间=1.698-9.355)、脑梗死位置左半球(OR=3.360,95%置信区间=1.454-7.764)、合并高尿酸血症(OR=3.213,95%置信区间=1.394-7.404)为影响AIS患者发生CI的高危因素(P<0.05且OR>1).结论AIS患者发生CI与年龄≥70岁、有吸烟史、合并糖尿病、NIHSS评分≥15分、脑梗死位置左半球、合并高尿酸血症关系密切,还需高度重视,并做好针对性干预,降低CI发生风险.
Objective To explore the related influencing factors and intervention measures of cognitive dysfunction(CI)in patients with acute ischemic stroke(AIS).Methods Clinical data of 104 patients with AIS admitted to Jiujiang First People’s Hospital from June 2021 to October 2023 were retrospectively analyzed.The cognitive function was assessed by the Montreal Cognitive Assessment Scale(MoCA)7 days after admission,and the AIS patients were divided into CI group and no CI group according to MoCA score.Age,sex,education,marital status,smoking history,drinking history,combined hyperlipidemia,combined diabetes,combined hypertension,National Health Study Stroke Scale(NIHSS)score,location of cerebral infarction,hyperuricemia and other basic data of the two groups were collected,and univariate analysis was performed first.Logistic regression analysis was performed after items with statistical differences were obtained,and the risk factors affecting the occurrence of CI in AIS patients were finally obtained.Results A total of 37 CI cases occurred in 104 patients,the incidence rate was 35.58%(37/104).There were significant differences in age,smoking history,diabetes mellitus,NIHSS score,location of cerebral infarction and hyperuricemia between the two groups(P<0.05).Multivariate results showed that age≥70 years old(OR=2.571,95%CI=1.120-5.905),history of smoking(OR=3.861,95%CI=1.657-8.994),combined diabetes(OR=2.481,95%CI=1.081-5.690),NIHSS score≥15 points(OR=3.986,95%confidence interval=1.698-9.355),cerebral infarction in the left hemisphere(OR=3.360,95%confidence interval=1.454-7.764),combined with hyperuricemia(OR=3.213,95%confidence interval=1.394-7.404)was a high risk factor for CI in AIS patients(P<0.05 and OR>1).Conclusion The incidence of CI in AIS patients is closely related to age≥70 years old,smoking history,diabetes mellitus,NIHSS score≥15,location of cerebral infarction in the left hemisphere,and hyperuricemia.Therefore,it is necessary to attach great importance to and make targeted interventions to reduce
作者
夏萌
杨云燕
邓燕
陈景玲
Xia Meng;Yang Yunyan;Deng Yan;Chen Jingling(Jiujiang First People’s Hospital,Jiujiang,Jiangxi 332000,China)
出处
《首都食品与医药》
2024年第15期22-24,共3页
Capital Food Medicine
关键词
急性缺血性脑卒中
认知功能障碍
影响因素
干预措施
Acute ischemic stroke
Cognitive dysfunction
Influencing factors
Intervention measure
