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WBC、CRP和ESR联合检测在小儿细菌性肺炎鉴别诊断中的价值

Value of WBC,CRP and ESR Combined Detection in Diagnosis and Differential Diagnosis of Bacterial Pneumonia of Children
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摘要 目的评估白细胞计数(WBC)、血沉(ESR)、C反应蛋白(CRP)及三者联合预测小儿细菌性肺炎的诊断效能。方法选取2019年10月—2020年11月本院收治的120例小儿肺炎住院患者为研究对象,根据是否为细菌感染分为细菌感染组(n=60)和非细菌感染组(n=60);比较两组患儿WBC、CRP和ESR水平,同时比较三项指标对于预测小儿细菌性肺炎效能。结果细菌感染组WBC为(18.1±4.8)×10~9/L、CRP为(56.7±25.7)mm/h、ESR为(44.0±34.6)mg/L,均高于非细菌感染组,组间差异有统计学意义(P<0.05)。预测小儿细菌性肺炎效能:WBC,曲线下面积(AUC)=0.48,P=0.000;ESR,AUC=0.927,P=0.000;CRP,AUC=0.948,P=0.000;上述三个定量指标联合,AUC=0.987,P=0.000。结论采用WBC、CRP和ESR联合检测预测小儿细菌性肺炎效能最佳,适宜作为常规检测指标模组,具有较高的推广应用价值。 Objective To evaluate diagnostic effect of white blood cell count(WBC),erythrocyte sedimentation rate(ESR),C-reactive protein(CRP)and its combination in predicting bacterial pneumonia of children.Methods The paper chose 120 hospitalized pneumonia children from October 2019 to November 2020,and divided them into bacterial infection group(n=60)and non bacterial infection group(n=60)based on condition bacteria infection.WBC,CRP and ESR levels were compared between two groups,while effect of three indicators in predicting bacterial pneumonia of children was compared.Results WBC was(18.1±4.8)×10^(9)/L,CRP was(56.7±25.7)mm/h,ESR was(44.0±34.6)mg/L in bacterial infection group,higher than non bacterial infection group(P<0.05).Predicting effect of bacterial pneumonia of children:WBC Area under curve(AUC)=0.48,P=0.000;ESR,AUC=0.927,P=0.000;CRP,AUC=0.948,P=0.000;Combination of three quantitative indicators:AUC=0.987,P=0.000.Conclusion Combined detection of WBC,CRP and ESR can achieve the best performance in predicting bacterial pneumonia of children,which can be a routine detection indicator module,with high promotion and application value.
作者 李玉 LI Yu(Laboratory Department,Dingzhou City People's Hospital,Dingzhou,Hebei 073000)
出处 《智慧健康》 2024年第13期79-81,共3页 Smart Healthcare
关键词 小儿肺炎 临床诊断 WBC CRP ESR 联合检测 Pneumonia of children Clinical diagnosis WBC CRP ESR Combined detection
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