摘要
目的探讨乳腺对比增强X线摄影(CESM)对乳腺良、恶性病变的鉴别诊断价值。方法选择超声检查或临床疑似乳腺疾病的患者67例(共72个病灶),均采用常规乳腺X线摄影(MG)、CESM检查。观察MG、CESM诊断乳腺良、恶性病变结果,以手术切除或活检获得的病理学结果作为金标准,绘制受试者工作特征(ROC)曲线,分析MG、CESM诊断效能,计算曲线下面积(AUC)值及灵敏度、特异度。结果67例患者(共72个病灶)经手术切除或活检获得病理学结果证实为恶性病灶、良性病灶各有42个、30个。乳腺恶性病变中以浸润性导管癌占比最高,为50.00%;乳腺良性病变以纤维腺瘤占比最高,为25.00%。以病理学结果作为金标准,CESM诊断乳腺良、恶性病变的AUC值(0.960)、灵敏度(0.966)、特异度(0.747)高于MG(0.844、0.897、0.609)。结论CESM可作为鉴别诊断乳腺良、恶性病变优选方法,其诊断乳腺癌灵敏度及特异度高于MG,对提升乳腺良、恶性病变鉴别诊断具有较高的效能。
Objective To investigate the value of contrast-enhanced spectral mammography(CESM)in the differential diagnosis of benign and malignant breast lesions.Methods A total of 67 patients(72 lesions)with ultrasonic or clinical suspected breast diseases were selected.All patients were examined by conventional mammography(MG)and CESM.The results of MG and CESM in the diagnosis of benign and malignant breast lesions were observed.The pathological results obtained by surgical resection or biopsy were used as the gold standard.The receiver operating characteristic(ROC)curve was drawn to analyze the diagnostic efficiency of MG and CESM,and the area under the curve(AUC),sensitivity and specificity were calculated.Results 67 patients(a total of 72 lesions)were pathologically confirmed as malignant lesions(42 lesions)and benign lesions(30 lesions)by surgical resection or biopsy.Among the malignant breast lesions,the proportion of invasive ductal carcinoma was the highest(50.00%).Among the benign breast lesions,the proportion of fibroadenoma was the highest(25.00%).Taking the pathological results as the gold standard,the AUC value(0.960),sensitivity(0.966)and specificity(0.747)of CESM in the diagnosis of benign and malignant breast lesions were higher than those of MG(0.844,0.897,0.609).Conclusion CESM can be used as an optimal method for the differential diagnosis of benign and malignant breast lesions.The sensitivity and specificity of CESM in the diagnosis of breast cancer are higher than those of MG,which has high differential diagnosis value of benign and malignant breast lesions.
作者
晏敏
付倩
马遥
黄丽萍
YAN Min;FU Qian;MA Yao(Nanchang Third People's Hospital,Nanchang,330009)
出处
《实用癌症杂志》
2024年第8期1347-1349,1376,共4页
The Practical Journal of Cancer
基金
江西省卫健委立项课题(编号:SKJP220217777)。
关键词
乳腺病变
乳腺对比增强X线摄影
常规乳腺X线摄影
诊断效能
Breast lesions
Contrast-enhanced spectral mammography
Conventional mammography
Diagnostic efficiency
