摘要
目的:探析内镜套扎术联合生长抑素治疗肝硬化食管静脉曲张出血患者的效果。方法:择取2020年1月—2023年9月贵航贵阳医院收治的72例肝硬化食管静脉曲张出血患者作为研究对象,随机分对照组和观察组,各36例。对照组给予内镜套扎术治疗,观察组在对照组基础上联合生长抑素治疗;比较两组临床指标(止血时间、输血总量及住院时间)、血流动力学指标(门静脉及脾静脉血流量)、并发症发生率及消化道再出血情况。结果:观察组总有效率高于对照组,差异有统计学意义(P<0.05)。观察组止血时间、住院时间均短于对照组,输血总量少于对照组,差异有统计学意义(P<0.05)。治疗后,两组门静脉血流量、脾静脉血流量均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。两组并发症总发生率比较,差异无统计学意义(P>0.05);观察组再出血率低于对照组,差异有统计学意义(P<0.05)。结论:内镜套扎术联合生长抑素治疗肝硬化食管静脉曲张出血患者效果显著,止血效果突出,有助于促进患者术后康复,降低术后再出血风险。
Objective:To explore the effect of endoscopic ligation combined with Somatostatin in the treatment of cirrhotic esophageal varices bleeding patients.Method:A total of 72 patients with cirrhotic esophageal varices bleeding treated in Guihang Guiyang Hospital from January 2020 to September 2023 were selected as the study objects,and randomly divided into control group and observation group,with 36 cases in each group.The control group was treated with endoscopic ligation and the observation group was treated with Somatostatin on the basis of control group.The clinical indexes(hemostatic time,total blood transfusion and hospital stay),hemodynamic indexes(portal vein and splenic vein blood flow),complication rate and gastrointestinal rebleeding were compared between the two groups.Result:The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).The hemostatic time and hospital stay in the observation group were shorter than those in the control group,and the blood transfusion volume was less than that in the control group,the differences were statistically significant(P<0.05).After treatment,portal vein blood flow and splenic vein blood flow in two groups were lower than those before treatment,and those in observation group were lower than those in control group,the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of complications between the two groups(P>0.05).The incidence of rebleeding in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion:Endoscopic ligation combined with Somatostatin is effective in patients with cirrhotic esophageal varices bleeding,which is helpful to promote postoperative rehabilitation and reduce the risk of postoperative rebleeding.
作者
武少林
WU Shaolin(Guihang Guiyang Hospital,Guiyang 550009,China)
出处
《中外医学研究》
2024年第19期104-108,共5页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
内镜套扎术
生长抑素
肝硬化
食管静脉曲张出血
并发症
Endoscopic ligation
Somatostatin
Cirrhosis
Esophageal varices bleeding
Complications
