摘要
目的了解社区40岁及以上中老年人肥胖状态与第1秒用力呼气容积(FEV_(1))下降的关联,为社区中老年人慢性呼吸系统疾病防治提供参考。方法基于2016年上海市郊区自然人群队列,于2021年采用随机抽样法抽取共3149名40岁及以上队列成员开展肺功能检查及问卷调查,根据体质指数(BMI)和腰围测量结果分为不同的肥胖类型。采用SPSS 22.0进行t检验、Mann-Whitney U检验、χ^(2)检验和多因素非条件logistic回归分析。结果3149名研究对象的FEV_(1)下降(FEV_(1)%Pred<80%)率为14.8%,男性(21.1%)高于女性(10.7%),差异有统计学意义(P<0.01)。研究对象的BMI超重率和肥胖率分别为43.7%和17.9%,中心性肥胖率为30.9%。多因素logistic回归分析结果显示,中心性肥胖与FEV_(1)下降高风险相关(OR=1.70),BMI超重(OR=0.63)或肥胖(OR=0.64)与FEV_(1)下降低风险相关,均有统计学意义(P<0.01)。在不同的肥胖类型中,BMI超重/肥胖+腰围正常者FEV_(1)下降的风险低于BMI偏瘦/正常+腰围正常者(OR=0.66),分性别分析后,男性居民中同样存在该关联(OR=0.63);BMI偏瘦/正常+中心性肥胖者的FEV_(1)下降风险高于BMI偏瘦/正常+腰围正常组(OR=1.93),该结果在女性中同样成立(OR=2.25),均有统计学意义(P<0.05)。结论中心性肥胖者相较于腰围正常者FEV_(1)下降率更高;而对于腰围正常者,BMI较低者FEV_(1)下降率更高。因此社区中老年人应调整生活方式以维持适当体重和减少腰围,从而预防肺功能下降。
Objective To understand the association of obesity status with force volume in 1 second(FEV_(1))reduction in community middle-aged and elderly adults(≥40 years old),and provide the reference for the prevention and treatment of chronic respiratory diseases in middle-aged and elderly adults in the communities.Methods Based on the 2016 Shanghai suburban natural population cohort,the random sampling method was used to select 3149 cohort members(≥40 years old)in 2021 as the subjects.The investigation was performed with pulmonary function examinations and questionnaires.The subjects were divided into different obesity types based on BMI and waist circumference measurements.The t test,Mann Witney U test,χ^(2) test and multifactorial unconditional logistic regression were used to analyze the data.The used software was SPSS 22.0.Results The rate of FEV_(1) reduction(FEV_(1)% Pred<80%)in the 3149 subjects was 14.8%,the FEV_(1) reduction rate(21.1%)in males was significantly higher than that(10.7%)in females(P<0.01).The BMI overweight and obesity rates of the subjects were 43.7% and 17.9%,respectively;and the central obesity rate was 30.9%.The results of multifactorial logistic regression analysis showed that central obesity was associated with a higher risk of FEV_(1) reduction(OR=1.70),and overweight(OR=0.63)or obesity(OR=0.64)of BMI was associated with lower risk of FEV_(1) reduction(P<0.01).In the different obesity types,the risk of lower FEV_(1) in those with overweight/obese BMI+normal waist circumference was lower than that in those with lean/normal BMI+normal waist circumference(OR=0.66),and the same association existed in the male population after subgender analysis(OR=0.63);the risk of lower FEV_(1) in those with lean/normal BMI+central obesity was higher than that in the group with lean/normal BMI+normal waist circumference(OR=1.93),the same result also existed in females(OR=2.25),P<0.05.Conclusion The rate of FEV_(1) reduction in residents with central obesity is higher than that in those with normal waist
作者
张艺璇
苏旭燕
侯珊珊
李静
尹欣
罗炜
俞敏君
臧金鑫
王伟
吴毅凌
赵琦
王琴
赵根明
姜永根
姜庆五
王娜
ZHANG Yixuan;SU Xuyan;HOU Shanshan;LI Jing;YIN Xin;LUO Wei;YU Minjun;ZANG Jinxin;WANG Wei;WU Yiling;ZHAO Qi;WANG Qin;ZHAO Genming;JIANG Yonggen;JIANG Qingwu;WANG Na(School of Public Health,Fudan University,Key Laboratory of Public Health Safety,Ministry of Education,Shanghai 200032,China;Department of Non-communicable Disease Prevention and Control,Songjiang District Center for Disease Control and Prevention,Shanghai 201600,China;不详)
出处
《中国慢性病预防与控制》
CAS
CSCD
北大核心
2024年第5期337-342,共6页
Chinese Journal of Prevention and Control of Chronic Diseases
基金
国家自然科学基金(82073634)
国家重点研发计划精准医学重点专项(2017YFC0907000)。
关键词
肥胖
第1秒用力呼气容积下降
肺功能检查
慢性阻塞性肺疾病
支气管哮喘
Obesity
Force volumn in 1 second reduction
Pulmonary function tests
Chronic obstructive pulmonary disease
Bronchial asthma
