摘要
目的分析重庆市九龙坡区肝癌疾病负担特征及变化趋势,为开展肝癌防治提供建议。方法收集2011-2021年重庆市九龙坡区肝癌发病死亡资料,计算肝癌发病率、中国人口年龄标化发病率(ASRIC)、死亡率、中国人口年龄标化死亡率(ASRMC)、伤残调整寿命年(DALY)、早死所致的寿命损失年(YLL)、伤残所致健康寿命损失年(YLD)等指标并进行分析。结果重庆市九龙坡区居民2011年肝癌粗发病率、ASRIC分别为28.58/10万、22.03/10万,2021年肝癌粗发病率、ASRIC分别为23.00/10万、15.51/10万。2011-2021年重庆市九龙坡区居民肝癌粗发病率、ASRIC的年度变化百分比(APC)分别为-1.39%(t=-1.707,P=0.122)和-2.76%(t=-3.095,P=0.013)。男性肝癌ASRIC的APC为-2.57%(t=-2.823,P=0.020);男性和女性粗发病率、ASRIC的趋势变化差异均无统计学意义(P>0.05)。历年肝癌发病率均为男性高于女性(P<0.05)。整体而言,人群肝癌发病率随年龄增长而升高。重庆市九龙坡区居民2011年肝癌粗死亡率、ASRMC分别为23.23/10万、18.44/10万,2021年肝癌粗死亡率、ASRMC分别为21.10/10万、20.84/10万。2011-2021年重庆市九龙坡区居民肝癌粗死亡率、ASRMC的APC分别为0.30%(t=0.284,P=0.783)和0.20%(t=0.127,P=0.901)。男性和女性粗死亡率、ASRMC趋势变化差异均无统计学意义(P>0.05)。历年肝癌死亡率均为男性高于女性(P<0.05)。整体而言,人群肝癌死亡率随年龄增长而升高。重庆市九龙坡区居民2011年肝癌YLD率、YLL率和DALY率分别为0.28千人年、7.97千人年和8.25千人年,2021年肝癌YLD率、YLL率和DALY率分别为0.21千人年、5.99千人年、6.20千人年。2011-2021年重庆市九龙坡区居民肝癌YLD率、YLL率和DALY率的APC分别为0.10%(t=0.064,P=0.951)、-2.27%(t=-1.837,P=0.099)、-2.18%(t=-1.799,P=0.106)。结论2011-2021年重庆市九龙坡区居民的肝癌疾病负担仍较重,尤其是男性和老年人群,YLL率较高是疾病负担过重的主要原�
Objective To analyze the characteristics and trends of liver cancer burden in Jiulongpo district,Chongqing,and provide suggestions for liver cancer prevention and control.Methods Data on liver cancer incidence and mortality from 2011 to 2021 in Jiulongpo District were collected.Incidence rate,age-standardized rate of incidence by Chinese standard population(ASRIC),mortality rate,age-standardized rate of incidence by world standard population(ASRIW),disability-adjusted life years(DALY),years of life lost(YLL),and years lived with disability(YLD)were calculated and analyzed.Results In 2011,the crude incidence rate and ASRIC of liver cancer in Jiulongpo district were 28.58/100000 and 22.03/100000,respectively.By 2021,these rates had decreased to 23.00/100000 and 15.51/100000,respectively.The annual percentage change(APC)for crude incidence rate and ASRIC from 2011 to 2021 was-1.39%(t=-1.707,P=0.122)and-2.76%(t=-3.095,P=0.013),respectively.For males,the APC for ASRIC was-2.57%(t=-2.823,P=0.020),but no significant trends were observed in crude incidence rates or female ASRIC(P>0.05).The incidence rates were consistently higher in males than females(P<0.05)and generally increased with age.The crude mortality rate and ASRMC in 2011 in this region were 23.23/100000 and 18.44/100000,respectively,and 21.10/100000 and 20.84/100000 in 2021,respectively.The APC for crude mortality rate and ASRMC from 2011 to 2021 in Jiulongpo district were 0.30%(t=0.284,P=0.783)and 0.20%(t=0.127,P=0.901).Regardless of gender,no significant trends were observed in crude mortality and ASRMC(P>0.05).Mortality rates were significantly higher in males than females over the years(P<0.05)and generally increased with age.In 2011,the YLD rate,YLL rate,and DALY rate in this district were 0.28,7.97,and 8.25 per 1000 person-years,respectively,and decreased to 0.21,5.99,and 6.20 per 1000 person-years by 2021.The APC for YLD rate,YLL rate,and DALY rate from 2011 to 2021 were 0.10%(t=0.064,P=0.951),-2.27%(t=-1.837,P=0.099),and-2.18%(t=-1.799,P=0.106),respec
作者
贺明
陶然
汤成
梁艳
马周俊
骆致
李小清
He Ming;Tao Ran;Tang Cheng;Liang Yan;Ma Zhoujun;Luo Zhi;Li Xiaoqing(Department of Chronic Non-communicable Disease and Endemic Disease Control,Chongqing Jiulongpo Center for Disease Control and Prevention,Chongqing 400039,China;Department of Hepatology,Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China)
出处
《保健医学研究与实践》
2024年第4期20-25,共6页
Health Medicine Research and Practice
基金
重庆市首批公共卫生重点专科(学科)建设项目(渝卫办发〔2022〕72号)
重庆市九龙坡区首批区级公共卫生重点专科(学科)建设项目(九龙坡卫办发〔2023〕63号)。
关键词
肝癌
疾病负担
发病率
死亡率
Liver cancer
Disease burden
Incidence rate
Mortality rate
