摘要
目的探讨糖尿病人群常规筛查中糖尿病性视网膜病变(diabetes retinopathy,DR)的影响因素。方法回顾性选取2022年1月—2023年12月于连云港市赣榆区人民医院进行常规筛查的450例糖尿病患者的临床资料。收集患者的基本信息,对比各项检查结果,筛查DR发生例数,分析DR发生的影响因素。结果450例糖尿病患者筛查出DR患者79例,其中非增生型DR 71例,增生型DR 8例。DR组和非DR组患者的性别、文化程度、人均月收入、烟酒史、家族史、总胆固醇、甘油三酯、高密度脂蛋白、低密度脂蛋白、血尿酸指标比较,差异无统计学意义(P均>0.05)。DR组和非DR组患者的病程、高血压、空腹血糖(fasting plasma glucose,FPG)、餐后2 h血糖、糖化血红蛋白(glycated hemoglobin A1c,HbA1c)、血肌酐、尿素氮指标比较,差异有统计学意义(P均<0.05)。Logistic回归分析显示,病程≥5年、FPG≥7.0 mmol/L、HbA1c≥6.5%是DR发生的独立危险因素(OR=1.600、2.203、2.261,P均<0.05)。结论糖尿病人群中DR发生率较高,病程长、血糖控制不佳是主要影响因素,提示医护人员重点关注此类人群,采取有效防治措施。
Objective To explore the influencing factors of diabetes retinopathy(DR)in routine screening of diabetes population.Methods The clinical data of 450 patients with diabetes who underwent routine screening in Ganyu District People's Hospital of Lianyungang from January 2022 to December 2023 were retrospectively selected.The basic information of the patients was collected,the results of various examinations were compared,the number of DR cases was screened,and the influencing factors of DR were analyzed.Results A total of 79 DR Patients were screened out from 450 diabetic patients,including 71 cases of non-proliferative DR and 8 cases of proliferative DR.There were no statistically significant differences in gender,education level,per capita monthly income,history of smoking and alcohol,family history,total cholesterol,triglyceride,high-density lipoprotein,low-density lipoprotein,and blood uric acid between DR group and non-DR group(all P>0.05).There were statistically significant differences in the course of disease,hypertension,fasting plasma glucose(FPG),2-hour postprandial plasma glucose,glycated hemoglobin A1c(HbA1c),serum creatinine and urea nitrogen between DR group and non-DR group(all P<0.05).Logistic regression analysis showed that the course of disease≥5 years,FPG≥7.0 mmol/L and HbA1c≥6.5%were independent risk factors for DR(OR=1.600,2.203,2.261,all P<0.05).Conclusion The incidence of DR in diabetes population is high,and the main influencing factors are long course of disease,and poor control of blood glucose.It suggests that medical staff should pay more attention to this population and take effective prevention and control measures.
作者
许荧
XU Ying(Department of Endocrinology,Ganyu District People's Hospital,Lianyungang 222100,Jiangsu,China)
出处
《糖尿病新世界》
2024年第9期169-172,共4页
Diabetes New World Magazine
关键词
糖尿病性视网膜病变
眼科检查
影响因素
血糖水平
Diabetes retinopathy
Ophthalmic examination
Influencing factors
Blood glucose levels
