摘要
目的 探讨注射用阿奇霉素治疗小儿支原体肺炎的临床效果。方法 选取2022年9月至2023年9月济南市儿童医院收治的92例支原体肺炎患儿作为研究对象,按照单双数法分为参照组与治疗组,每组各46例。参照组采用常规治疗,治疗组在参照组基础上采用注射用阿奇霉素治疗。比较两组炎症因子水平、症状恢复时间及临床疗效。结果 治疗后,两组肿瘤坏死因子-α、白介素-6、超敏C反应蛋白水平均低于治疗前,且治疗组水平低于参照组,差异有统计学意义(P <0.05)。治疗组咳嗽、发热、胸部X线检查及肺部啰音恢复时间均短于参照组,差异有统计学意义(P<0.05)。治疗组临床总有效率为97.83%,高于参照组的82.61%,差异有统计学意义(P <0.05)。结论 注射用阿奇霉素治疗小儿支原体肺炎的临床效果较好,可缩短症状恢复时间,减轻炎症反应,对小儿支原体肺炎较适用。
Objective To explore the clinical effect of Azithromycin for Injection in the treatment of pediatric Mycoplasma pneumonia.Methods A total of 92 children with Mycoplasma pneumonia admitted to the Department of Pharmacy,Jinan Children’s Hospital from September 2022 to September 2023 were selected as the study subjects.All the children were divided into the reference group and the treatment group according to the odd and even number method,with 46 cases in each group.The reference group was given routine treatment,while the treatment group was treated with Azithromycin for Injection on the basis of the reference group.The levels of inflammatory factors,symptom recovery time,and clinical efficacy were compared between the two groups.Results After treatment,the tumor necrosis factor-α,interleukin-6,and hypersensitive C-reactive protein in both groups were lower than those before treatment,and the levels in the treatment group were lower than those in the reference group,and the differences were statistically significant(P<0.05).The recovery time of cough,fever,chest X-ray,and lung rales in the treatment group was shorter than that in the reference group,and the difference was statistically significant(P<0.05).The total clinical effective rate in the treatment group was 97.83%,which was higher than 82.61%in the reference group,and the difference was statistically significant(P<0.05).Conclusion The clinical effect of Azithromycin for Injection in the treatment of pediatric Mycoplasma pneumonia is good,and can shorten the recovery time of symptoms,reduce inflammation reactions,and is more suitable for pediatric Mycoplasma pneumonia.
作者
明洁
MING Jie(Department of Pharmacy,Jinan Children’s Hospital,Shandong Province,Jinan 250022,China)
出处
《妇儿健康导刊》
2024年第13期87-90,共4页
JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE
关键词
注射用阿奇霉素
小儿支原体肺炎
炎症因子
Azithromycin for Injection
Pediatric Mycoplasma pneumonia
Inflammatory factor
