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经阴道三维彩超联合血β-人绒毛膜促性腺激素对早期宫外孕的诊断价值

Diagnostic value of transvaginal three-dimensional color Doppler ultrasound combined with blood β-human chorionic gonadotropin for early ectopic pregnancy
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摘要 目的探讨经阴道三维彩超联合血β-人绒毛膜促性腺激素(β-hCG)对早期宫外孕的诊断价值。方法选取2020年8月至2023年9月安庆市第一人民医院收治的80例早期宫外孕患者作为研究对象,设为观察组。另选取同期80例宫内孕孕妇设为对照组。分析两组超声指标与血β-hCG水平;绘制超声指标、血β-hCG单独及联合诊断早期宫外孕的受试者工作特征(ROC)曲线;通过病理结果分析经阴道三维彩超联合血β-hCG诊断的准确性。结果两组阻力指数、搏动指数、收缩期峰值流速比较,差异无统计学意义(P>0.05);观察组子宫内膜厚度、血β-hCG水平均小于对照组,差异具有统计学意义(P<0.05)。ROC曲线结果显示,子宫内膜厚度、血β-HCG及两者联合诊断宫外孕的曲线下面积分别为0.833、0.877及0.975(P<0.05)。与病理结果比较,经阴道三维彩超联合血β-hCG诊断漏诊、误诊5例,诊断准确率为93.75%。结论经阴道三维彩超联合血β-hCG对早期宫外孕具有较高的诊断价值,可为临床快速准确诊断早期宫外孕提供可靠信息。 Objective To investigate the diagnostic value of transvaginal three-dimensional color Doppler ultrasound combined with bloodβ-human chorionic gonadotropin(β-hCG)for early ectopic pregnancy.Methods A total of 80 patients with early ectopic pregnancy who were admitted to Anqing First People′s Hospital from August 2020 to September 2023 were selected as study objects and set as the observation group.Meanwhile,80 cases of intrauterine pregnancies during the same period were selected as the control group.Ultrasound parameters and bloodβ-hCG levels in the two groups were analyzed.The receiver operating characteristic(ROC)curves of ultrasound parameters,bloodβ-hCG,and their combination for diagnosing early ectopic pregnancy were plotted.The diagnostic accuracy of transvaginal three-dimensional color Doppler ultrasound combined with bloodβ-hCG was analyzed based on pathological results.Results There were no statistically significant differences in resistance index,pulsatility index,and peak systolic velocity between the groups(P>0.05).The endometrial thickness and bloodβ-hCG level of the observation group were smaller/lower than those of the control group(P<0.05).ROC curve analysis results showed that the areas under the curves of endometrial thickness,bloodβ-hCG,and their combination for diagnosing ectopic pregnancy were 0.833,0.877 and 0.975,respectively(P<0.05).Compared with pathological results,5 cases were missed diagnosis and misdiagnosed by transvaginal three-dimensional color Doppler ultrasound combined with bloodβ-hCG.The diagnostic accuracy was 93.75%.Conclusions Transvaginal three-dimensional color Doppler ultrasound combined with bloodβ-hCG has relatively high diagnostic value for early ectopic pregnancy,and can provide reliable information for clinical rapid and accurate diagnosis of early ectopic pregnancy.
作者 刘玉净 鲁育民 胡金花 黄菊霞 余奕 程扬眉 LIU Yujing;LU Yumin;HU Jinhua;HUANG Juxia;YU Yi;CHENG Yangmei(Department of Utrasound,Anqing First People's Hospital,Anqing 246000,Anhui,China;Department of Hepatobiliary Surgery,Anqing First People's Hospital,Anqing 246000,Anhui,China)
出处 《中国性科学》 2024年第7期79-82,共4页 Chinese Journal of Human Sexuality
基金 安徽省高校自然科学研究项目(KJ2021A0344)。
关键词 经阴道三维彩超 血Β-人绒毛膜促性腺激素 早期宫外孕 诊断价值 Transvaginal three-dimensional color Doppler ultrasound Bloodβ-human chorionic gonadotropin Early ectopic pregnancy Diagnostic value
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