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155名捐精志愿者精液质量参数分析

Analysis of semen quality parameters among 155 sperm donors
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摘要 目的 分析捐精志愿者各项精液质量参数,为男性不育防治及相关研究提供参考。方法 2021年1—3月采用方便抽样方法抽取浙江省人类精子库155名捐精志愿者为研究对象,通过问卷调查收集人口学资料;采集精液检测精液体积、精子浓度、精子总数、精子前向运动率和精子活力等参数,参考《世界卫生组织第5版人类精液检查实验室手册》评价精液质量合格情况。结果 155名捐精志愿者的年龄M (QR)为24 (7)岁;未婚127人,占81.94%;无工作97人,占62.58%;本科及以上学历91人,占58.71%;体质指数≥25 kg/m^(2)42人,占27.09%。捐精志愿者的禁欲时间、精子总数、精液体积、精子浓度、精子前向运动率和精子活力的M (QR)分别为4 (1) d、51 (38)×10^(6)/1次射精、3.90 (2.20) mL、204.60 (161.30)×10^(6)/mL、47%(10%)和50%(11%);不合格率分别为0%、0.65%、1.29%、4.52%、9.68%和18.06%。总体精液质量不合格32人,不合格率为20.65%。结论 155名捐精志愿者中有20.65%总体精液质量不合格,以精子前向运动率和精子活力的不合格率相对较高。 Objective To analyze the semen quality parameters of sperm donor volunteers,so as to provide insights into male infertility control and related research.Methods A total of 155 sperm donors were recruited from the Human Sperm Bank of Zhejiang Province using the convenience sampling method from January to March 2021.Demographic information were collected through questionnaire surveys.Semen were collected,and parameters including semen volume,sperm concentration,total number of sperm,forward motility rate and total sperm viability were measured.Semen quality was evaluated according to the WHO Laboratory Manual for the Examination and Processing of Human Semen.Results Among 155 sperm donors,127 were unmarried(81.94%),97 were unemployed(62.58%),91 had a bachelor's degree and above(58.71%),and 42 had a body mass index of 25 kg/m^(2) and above(27.09%).The median age was 24(interquartile range,7)years.The median(interquartile range)abstinence time,total number of sperm,semen volume,sperm concentration,forward motility rate and total sperm viability were 4(1)d,51(38)×10^(6)/1 ejaculation,3.90(2.20)mL,204.60(161.30)×10^(6)/mL,47%(10%)and 50%(11%),and the unqualified rates were 0%,0.65%,1.29%,4.52%,9.68%and 18.06%,respectively.The overall unqualified rates of semen quality was 20.65%.Conclusion There were 20.65%of the 155 sperm donors with unqualified semen,and the unqualified rates of forward motility rate and total sperm viability were relatively high.
作者 黄婧 蒋兆强 阮征 李涛 盛慧强 李佳萍 楼建林 HUANG Jing;JIANG Zhaoqiang;RUAN Zheng;LI Tao;SHENG Huiqiang;LI Jiaping;LOU Jianlin(School of Public Health,Hangzhou Medical College,Hangzhou,Zhejiang 310013,China;Human Sperm Bank of Zhejiang Maternal,Child and Reproductive Health Center,Hangzhou,Zhejiang 310013,China;Huzhou Normal University,Huzhou,Zhejiang 313000,China;The First Affiliated Hospital of Huzhou Normal University,Huzhou,Zhejiang 313000,China)
出处 《预防医学》 2024年第7期632-635,共4页 CHINA PREVENTIVE MEDICINE JOURNAL
基金 浙江省基础公益研究计划项目(LTGY23H260008) 浙江省公共卫生与预防医学重点学科A类一流学科项目(KYYB202113) 杭州医学院研究生课程建设项目(26100548304-21) 浙江省医药卫生科技计划项目(2023KY664,2023KY654)。
关键词 捐精志愿者 精液质量 生殖健康 sperm donor semen quality reproductive health
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