摘要
目的 探讨缩宫素联合卡前列甲酯栓(商品名:卡孕栓)对经阴道分娩试产高危产妇产后出血的防治效果。方法 70例待产且接受阴道分娩试产的高危产妇,应用随机数字表法将其分成对照组和研究组,各35例。对照组产妇应用缩宫素,研究组产妇应用缩宫素联合卡孕栓。对比两组产程时间、产后出血量、产后出血发生情况、凝血指标[凝血酶时间(TT)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)]、血常规指标、心理状态评分。结果 两组第一产程、第二产程时间对比均未发现明显差异(P>0.05);研究组第三产程时间(8.34±1.18)min比对照组的(10.92±1.54)min短(P<0.05)。研究组产后2 h出血量(336.43±65.74)ml、产后24 h出血量(413.16±49.07)ml均比对照组的(389.81±58.92)、(493.49±72.34)ml少,产后出血发生率2.86%比对照组的17.14%低(P<0.05)。干预后,两组TT、PT、APTT与干预前对比均显著延长,但研究组TT、PT、APTT均比对照组短(P<0.05)。干预后,两组血红蛋白、红细胞计数相比干预前均显著降低,但研究组血红蛋白(121.53±3.41)g/L及红细胞计数(3.79±0.45)×10^(12)/L均比对照组的(116.85±3.28)g/L、(3.28±0.39)×10^(12)/L高(P<0.05)。干预后,两组焦虑和抑郁评分均较干预前显著降低,且研究组焦虑和抑郁评分均较对照组更低(P<0.05)。结论 对经阴道分娩试产的高危产妇联用缩宫素与卡孕栓可加快第三产程进展,有效预防与治疗产后出血,并对凝血功能、血常规指标影响减小,有利于减轻产妇产后的负性情绪。
Objective To explore the effect of oxytocin combined with carboprost suppositories in the prevention of postpartum hemorrhage after trial of vaginal delivery in high-risk parturients.Methods 70 high-risk parturients undergoing trial of vaginal delivery were selected.A random number table method was used to divide them into a control group and a study group,with 35 cases in each group.The control group was treated with oxytocin,while the study group was treated with oxytocin combined with carboplatin suppositories.Comparison was made on the duration of labor,amount of postpartum bleeding,occurrence of postpartum bleeding,coagulation index[thrombin time(TT),prothrombin time(PT),activated partial thromboplastin time(APTT)],blood routine index and psychological score between the two groups.Results There was no significant difference in the duration of the first and second stages of labor between the two groups(P>0.05).The duration of the third stage of labor in the study group was(8.34±1.18)min,which was shorter than(10.92±1.54)min in the control group(P<0.05).The amount of postpartum bleeding at 2 and 24 h postpartum were(336.43±65.74)and(513.16±49.07)ml,which were lower than(389.81±58.92)and(493.49±72.34)ml in the control group;the study group had incidence of postpartum hemorrhage of 2.86%,which was lower than 17.14%in the control group(P<0.05).After intervention,TT,PT and APTT in both groups were significantly longer than those before intervention,but TT,PT and APTT in the study group were shorter than those in the control group(P<0.05).After intervention,the hemoglobin and red blood cell count in both groups were significantly reduced compared with those before intervention;however,the study group had hemoglobin of(121.53±3.41)g/L and red blood cell count of(3.79±0.45)×10^(12)/L,which were higher than(116.85±3.28)g/L and(3.28±0.39)×10^(12)/L in the control group(P<0.05).After intervention,the scores of anxiety and depression in both groups were significantly lower than those before intervention,and t
作者
舒静静
SHU Jing-jing(Jinxiang County People's Hospital,Jining 272200,China)
出处
《中国实用医药》
2024年第12期30-33,共4页
China Practical Medicine
关键词
阴道分娩
产后出血
卡前列甲酯栓
缩宫素
Vaginal delivery
Postpartum hemorrhage
Carboprost suppositories
Oxytocin
