摘要
目的:观察中药熏蒸联合清胰汤加减内服治疗轻症急性胰腺炎的临床疗效。方法:选择100例轻症急性胰腺炎患者为研究对象,按随机数字表法分为观察组和对照组各50例。对照组给予奥曲肽治疗,观察组在对照组治疗基础上给予中药熏蒸及清胰汤内服治疗,两组均连续治疗14天。观察两组治疗前后中医证候积分、血清炎症因子、血清淀粉酶、全身炎症反应综合征评分、急性胰腺炎严重程度指标评分的变化情况,以及临床症状消失时间、临床疗效及安全性。结果:治疗后,两组中医证候积分均低于治疗前(P<0.05),且观察组低于对照组(P<0.05)。治疗后,两组血清炎症因子、血清淀粉酶水平、全身炎症反应综合征评分、急性胰腺炎严重程度指标评分均较治疗前下降(P<0.05),且观察组均低于对照组(P<0.05)。观察组临床症状消失时间均明显短于对照组(P<0.05);观察组总有效率[98.00%(49/50)]高于对照组[84.00%(42/50)](P<0.05);两组在治疗过程中均未发生不良反应。结论:采用中药熏蒸联合加减清胰汤内服治疗轻症急性胰腺炎,能够明显减轻患者临床症状,缩短病程,降低患者血清炎性因子、AMS等实验室指标,并提升临床疗效。
Objective:To observe the clinical efficacy of traditional Chinese medicine fumigation combined with internal administration of modified Qingyi Tang(Pancreas-clearing decoction)in the treatment of mild acute pancreatitis.Methods:All 100 patients with mild acute pancreatitis were selected as study subjects and divided into 50 cases each in the observation group and control group according to the randomized numerical table method.The control group was treated with octreotide,and the observation group accepted traditional Chinese medicine fumigation and internal administration of Qingyi Tang on the basis of the control group,and both groups were treated continuously for 14 days.To observe TCM syndrome integrals,serum inflammatory factor,serum amylase,systemic inflammatory response syndrome score,acute pancreatitis severity index score before and after the treatment of the two groups,as well as the disappearance time of clinical symptoms,clinical efficacy and safety.Results:After treatment,the TCM syndrome scores of both groups were lower than these before treatment(P<0.05),and the observation group was lower than the control group(P<0.05).After treatment,the levels of serum inflammatory factor,serum amylase,systemic inflammatory response syndrome scores,and acute pancreatitis severity index score of both groups were lower than theses before treatment(P<0.05),and the observation group was lower than the control group(P<0.05).The time for the disappearance of clinical symptoms in the observation group was significantly shorter than that in the control group(P<0.05);the total effective rate of the observation group was[98.00%(49/50)],higher than that[84.00%(42/50)]of the control group(P<0.05);and no adverse reactions occurred in the course of the treatment in both groups.Conclusion:The application of traditional Chinese medicine fumigation combined with internal administration of Qingyi Tang in the treatment of mild acute pancreatitis can noticeably reduce the clinical symptoms of patients,shorten the course of the dise
作者
李军
陈连锁
李树峰
任意
庞英
LI Jun;CHEN Liansuo;LI Shufeng;REN Yi;PANG Ying(Huanghua Municipal People's Hospital,Huanghua 061100,China)
出处
《西部中医药》
2024年第6期134-137,共4页
Western Journal of Traditional Chinese Medicine
基金
河北省中医药管理局科研计划(2017286)。
关键词
胰腺炎
急性
轻症
清胰汤
奥曲肽
中药熏蒸
中医证候积分
随机对照试验
pancreatitis,acute,mild
Qingyi Tang
octreotide
Traditional Chinese medicine fumigation
Traditional Chinese medicine syndrome integrals
randomized controlled trials
