摘要
通过仝小林院士治疗甲状腺功能亢进症验案1则,阐述黄药子“随证施量”策略在甲状腺功能亢进症治疗中的应用:黄药子治疗甲亢的常用剂量为9~15 g,患者病势轻重程度决定用药剂量;根据患者服用后“症靶”及“标靶”的改善程度调整用量;毒性药物需配伍减毒药物以减轻其毒性反应,两者用量呈正比关系,并在用药过程中实时监测相关指标变化,及时减量或停药;基于病情,权衡疗效和不良反应之间的关系,精准把控毒性药物在治疗中的“剂量阈”。
This article elaborates on the application of the"determining dosage according to syndromes"strategy by presenting a case of air potato in the treatment of hyperthyroidism by Academician Tong Xiaolin.The strategy can be generalized as the following four aspects:The common dosage range of air potato for the treatment of hyperthyroidism is 9-15g,and the dosage is determined according to the severity of the disease.Next,the dosage should be adjusted according to the improvement degree of the symptom targets and biochemical indicator targets after a patient takes the medicine.Thirdly,air potato,a herb with toxicity,needs to be paired with toxicity-reducing herbs to reduce its toxicity,and their dosages are proportional to each other,and a real-time monitoring should be in place on the changes in relevant indicators during the treatment,with a timely dosage reduction or stop of the drug if necessary.Lastly,based on the condition of a patient,the relationship should be weighed between the efficacy and toxicity of air potato,and the"dosage threshold"of toxic drugs should be accurately controlled during the treatment.
作者
陈钰冰
谢晓燕
姬航宇
连凤梅
李昀熹
徐诗晴
李艳
杨玲玲
CHEN Yubing;XIE Xiaoyan;JI Hangyu;LIAN Fengmei;LI Yunxi;XU Shiqing;LI Yan;YANG Lingling(The Second Clinical Medical College of Guangzhou University of Chinese Medicine,Guangzhou 510006,China;Department of Psychological Sleep,Guangdong Hospital of Traditional Chinese Medicine,Guangzhou 510120,China;Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China)
出处
《吉林中医药》
2024年第6期664-667,共4页
Jilin Journal of Chinese Medicine
基金
国家自然科学基金资助项目(82305167)
国家自然科学基金(81274000)
广东省基础与应用基础研究基金项目(2023A1515220036)
广东省中医药局科研项目(20223036)
广东省中医药局科研项目(20242028)
市校(院)联合资助项目(SL2022A03J0097)
市校(院)联合资助项目(2023A03J0740)
国家重点基础研究发展计划(973计划)项目(2010CB530601)
国家中医药管理局“中医药循证能力提升项目”(国中医药科技中药便函[2023]24号)
仝小林学术经验传承工作室(中医二院[2022]106号)。
关键词
随证施量
黄药子
甲状腺功能亢进症
strategy of determining dosage according to syndromes
air potato
hyperthyroidism
