摘要
间充质干细胞具有强大的自我更新、多向分化和旁分泌能力,在肾脏疾病的治疗中展现出了良好的应用前景。本文综述了间充质干细胞在肾脏损伤修复中的作用机制,旨在为间充质干细胞的临床应用提供参考依据。
Mesenchymal stem cells (MSCs) are a kind of cells with robust self-renewal, multi-lineage differentiation, and paracrine potential, having a good application prospect in the treatment of renal diseases. This article reviewed the mechanism of MSCs in the repair of renal injury, aiming to provide reference for future clinical application of MSCs.
作者
付章宁
耿晓东
张永军
陆宇平
孙冠南
张益帆
蔡广研
陈香美
洪权
Fu Zhangning;Geng Xiaodong;Zhang Yongjun;Lu Yuping;Sun Guannan;Zhang Yifan;Cai Guangyan;Chen Xiangmei;Hong Quan(Chinese PLA Medical School,Bejing 100853;Department of Nephrology,First Medical Center of Chinese PLA General Hospital,National Key Laboratory of Kidney Diseases,National Clinical Research Center for Kidney Diseases,Beijing Key Laboratory of Kidney Diseases,Beijing 100853;Healthcare Office of Service Bureau,Agency for Offices Administration,Central Military Commission of People's Republic of China,Bejing 100034,China)
出处
《中华肾病研究电子杂志》
2024年第2期87-91,共5页
Chinese Journal of Kidney Disease Investigation(Electronic Edition)
基金
国家重点研发计划项目(2018YFE0126600)
国家自然科学基金面上项目(82070741,82204744,82270758)。
关键词
肾脏疾病
间充质干细胞
肾脏再生
旁分泌
Renal disease
Mesenchymal stem cells
Renal regeneration
Paracrine