摘要
目的探索乌鲁木齐市子痫前期对孕妇及新生儿结局的影响。方法回顾性收集2021年2月至2023年2月乌鲁木齐市妇幼保健院分娩的子痫前期患者1000例作为子痫前期组,选取同期产检无子痫前期孕妇4308例作为对照组,采用单因素比较分析子痫前期组与对照组的妊娠结局。利用主成分分析法消除各因素之间的相关性,运用Logistic回归进行妊娠结局分析。结果子痫前期组与对照组妊娠结局与并发症比较,子痫前期组不良妊娠结局与并发症的发生率高于子痫前期组,子痫前期组不同分娩方式妊娠结局比较,剖宫产的胎儿不良妊娠结局发生率高于自然分娩;子痫前期组足月产与早产妊娠结局比较,早产不良妊娠结局发生率高于足月产不良妊娠结局;通过主成分分析子痫前期组妊娠结局中所有变量相关情况,共提取了3个公因子,累计贡献率达到67.413%。结论子痫前期对孕妇及新生儿结局造成了不良影响,子痫前期与胎儿生长发育迟缓呈正相关关系,子痫前期孕妇发生绒毛膜羊膜炎会更容易发生产褥期感染、早产、产后出血等不良妊娠结局,应尽早采取干预措施预防其进一步进展,做到早发现、早干预、早治疗,改善母婴结局。
Objective To explore the impact of preeclampsia on maternal and neonatal outcomes in Urumqi.Methods 1000 cases of preeclamptic patients delivered in Urumqi Maternal and Child Health Hospital from February 2021 to February 2023 were retrospectively collected as the preeclampsia group,and 4308 cases of pregnant women without preeclampsia in the same period of obstetrics examination were selected as the control group,and the pregnancy outcomes of the preeclampsia group and the normal group were analyzed by one-way comparison.The correlation between the factors was eliminated by principal component analysis,and the pregnancy outcomes were analyzed by Logistic regression.Results Comparing the pregnancy outcomes and complications between the preeclampsia group and the normal group,the incidence of adverse pregnancy outcomes and complications was higher in the preeclampsia group than in the preeclampsia group.Comparing the pregnancy outcomes of the preeclampsia group with different modes of delivery,the incidence of fetal adverse pregnancy outcomes was higher in cesarean section than in spontaneous delivery;and comparing the pregnancy outcomes of the preeclampsia group with those of the full-term and preterm deliveries,the incidence of preterm deliveries was higher than that of the term deliveries.By analyzing the correlation of all variables in pregnancy outcomes in the preeclampsia group through principal component analysis,a total of three common factors were extracted with a cumulative contribution of 67.413%.Conclusion Pre-eclampsia adversely affects maternal and neonatal outcomes,and there is a positive correlation between pre-eclampsia and fetal growth retardation.Pre-eclamptic pregnant women with chorioamnionitis are more likely to have adverse pregnancy outcomes such as puerperal infections,preterm labor,and post-partum hemorrhage,so early intervention should be taken to prevent its further progression,and to achieve early detection,intervention,and treatment,so as to improve the outcomes of mothers and infants
作者
程备
段茉莉
丁桂凤
CHENG Bei;DUAN Moli;DING Guifeng(School of Public Health,Xinjiang Medical University,Urumqi,Xinjiang 830000,China;Urumqi Maternal and Child Health Hospital,Urumqi,Xinjiang 830000,China)
出处
《中国优生与遗传杂志》
2024年第3期497-502,共6页
Chinese Journal of Birth Health & Heredity
基金
新疆维吾尔自治区自然科学基金项目(2022D01A29)。
关键词
子痫前期
妊娠结局
分娩方式
主成分分析
preeclampsia
pregnancy outcome
mode of delivery
principal component analysis
