摘要
目的分析氟伏沙明联合认知行为疗法治疗儿童青少年情绪障碍的疗效。方法将2020年1月至2022年12月新疆医科大学第一附属医院儿童青少年情绪障碍患儿(100例)设置为研究对象,按照随机单双数抽签法分组(抽到单数入对照组、抽到双数入研究组),各50例,对照组应用单一氟伏沙明治疗,研究组采取氟伏沙明+认知行为疗法治疗。比较两组治疗前后儿童抑郁障碍自评量表(DSRSC)评分、儿童焦虑性情绪障碍筛查表(SCARED)评分、儿童大体评定量表(CGAS)评分及儿童青少年生活质量量表(QLSCA)评分。结果治疗前两组DSRSC、SCARED评分对比差异无统计学意义(P>0.05),治疗后两组DSRSC、SCARED评分较治疗前均降低,且研究组评估分值低于对照组,差异均有统计学意义(P<0.05);治疗前两组CGAS评分对比差异无统计学意义(P>0.05),治疗后两组CGAS评分较治疗前均升高,且研究组评估分值高于对照组,差异均有统计学意义(P<0.05);治疗前两组QLSCA各维度评分对比差异无统计学意义(P>0.05),治疗后两组QLSCA各维度评分较治疗前均升高,且研究组评估分值高于对照组,差异均有统计学意义(P<0.05)。结论儿童青少年情绪障碍采用氟伏沙明+认知行为治疗可取得较理想的抗焦虑、抗抑郁的治疗效果,同时可提升生活质量,值得应用。
Objective To analyze the efficacy of fluvoxamine combined with cognitive-behavioral therapy in treating mood disorders in children and adolescents.Methods A total of 100 cases of children and adolescents with mood disorders were selected from the First Affiliated Hospital of Xinjiang Medical University between January 2020 and December 2022 as subjects for the study.The subjects were grouped according to a random odd-even lottery method.A random number generator was used to determine the allocation of cases into the control and research groups.Each group comprised 50 cases,and the control group received a single fluvoxamine treatment,while the research group received fluvoxamine in combination with cognitive behavioral therapy.The two groups were compared before and after treatment with the scores of the following instruments:the Children's Depression Rating Scale(CDRS),the Screen for Child Anxiety Related Emotional Disorders(SCARED),the Children's Global Assessment Scale(CGAS),and the Children's and Adolescents'Quality of Life Scale(QLSCA).Results The difference between the DSRSC and SCARED scores of the two groups before treatment was not statistically significant(P>0.05).However,the DSRSC and SCARED scores of the two groups after treatment were lower than before treatment.Furthermore,the assessment scores of the research group were lower than those of the control group,and the difference was statistically significant(P<0.05).5)The difference between the CGAS scores of the two groups before treatment was not statistically significant(P>0.05),and after treatment,the CGAS scores of the two groups were higher than before treatment.The assessment scores of the research group were higher than those of the control group,and the differences were statistically significant(P<0.05).The scores of the QLSCA dimensions between the two groups before treatment were not statistically significant(P>0.05).However,the scores of the QLSCA dimensions of the two groups after treatment were higher than those of the pre-treatment peri
作者
丽扎·满苏尔
罗晓
LIZHA Mansuer;LUO Xiao(Psychological Medicine Center,First Affiliated Hospital of Xinjiang Medical University,Urumqi Xinjiang 830054,China)
出处
《临床研究》
2024年第6期72-75,共4页
Clinical Research
关键词
氟伏沙明
认知行为治疗
儿童青少年情绪障碍
fluvoxamine
cognitive behavioral therapy
emotional disorder in children and adolescents
