摘要
目的:分析复方甲氧那明胶囊联合常规对症治疗在支气管哮喘急性发作期的应用效果。方法:选取2022年6月—2023年6月中国人民解放军第九四三医院收治的支气管哮喘急性发作期患者88例作为研究对象,依据随机数字表法分为对照组与观察组,各44例。对照组采取常规对症治疗,观察组在对照组基础上应用复方甲氧那明胶囊。比较两组治疗效果。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P=0.007)。治疗后,两组用力肺活量、第1秒用力呼气容积及1秒率高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05)。治疗后,两组生活质量评分高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05)。两组不良反应总发生率比较,差异无统计学意义(P=0.645)。结论:复方甲氧那明胶囊联合常规对症治疗在支气管哮喘急性发作期的应用效果较好,可改善患者肺功能指标及生活质量,且不会增加不良反应,值得推广。
Objective:To analyze the application effect of compound methoxyphenamine hydrochloride capsules combined with conventional symptomatic treatment for acute attack of bronchial asthma.Methods:A total of 88 patients with acute attack of bronchial asthma admitted to the 943rd Hospital of Chinese People's Liberation Army from June 2022 to June 2023 were selected as the study subjects.They were divided into control group and observation group according to random number table method,with 44 cases in each group.The control group was given conventional symptomatic treatment,and the observation group was treated with compound methoxyphenamine hydrochloride capsules on the basis of the control group.The therapeutic effect of the two groups was compared.Results:The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P=0.007).After treatment,the forced vital capacity,the forced expiratory volume in 1 second and the percentage of forced expiratory volume in 1 second in the two groups were higher than those before treatment,and these indexes in the observation group were higher than those in the control group,with a statistically significant difference(P<0.05).After treatment,the quality of life score in the two groups was higher than that before treatment,and the score in the observation group was higher than that in the control group,with a statistically significant difference(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P=0.645).Conclusion:The application effect of compound methoxyphenamine hydrochloride capsules combined with conventional symptomatic treatment for acute attack of bronchial asthma is good,which can improve the lung function index and quality of life of patients,and will not increase adverse reactions,which is worthy of promotion.
作者
王宏生
权卓
任长寿
Wang Hongsheng;Quan Zhuo;Ren Changshou(Respiratory Department,The 943rd Hospital of Chinese People's Liberation Army,Wuwei 733000,Gansu Province,China)
出处
《中国社区医师》
2024年第9期32-34,共3页
Chinese Community Doctors
关键词
复方甲氧那明胶囊
支气管哮喘
急性发作期
肺功能
Compound methoxyphenamine hydrochloride capsules
Bronchial asthma
Acute attack stage
Lung function