摘要
阿比多尔(ARB)具有广泛的抗病毒作用,被各大指南推荐用于甲型、乙型流感的治疗。本文回顾了ARB抗病毒作用机理、药物代谢动力学、生物等效性以及在抑制流感病毒、严重急性呼吸综合征病毒、中东呼吸综合征病毒、埃博拉病毒的临床研究现状,然后对ARB相关药物不良反应(ADR)防范及ARB超药品说明书用药的医学伦理进行了分析,以期为后续临床研究和应用提供参考。
Abidorel(ARB)has a wide range of antiviral effects and is recommended for the treatment of influenza A and B by major guidelines.In this paper,the antiviral mechanism,pharmacokinetics,bioequivalence of ARB and its clinical research status in inhibiting influenza virus,severe acute respiratory syndrome virus,Middle East respiratory syndrome virus and Ebola virus are reviewed.Then,the prevention of ARB-related adverse drug reactions(ADR)and the medical ethics of ARB drug instructions are analyzed in order to provide reference for subsequent clinical research and application.
作者
陈方方
张乾元
张红旭
CHEN Fang-fang;ZHANG Qian-yuan;ZHANG Hong-xu(Department of Pharmacy,Xuzhou Tumor Hospital,Xuzhou 221005,Jiangsu,China;Xuzhou No.1 Middle School,Xuzhou 221004,Jiangsu,China)
出处
《医学信息》
2024年第9期188-192,共5页
Journal of Medical Information
基金
江苏省徐州市卫健委药学科研项目(编号:XWYXKY202207)。
