摘要
目的探讨腹腔镜辅助阴式全子宫切除术在巨大子宫肌瘤治疗中的应用价值。方法选取2020年1月至2021年2月济南市第一人民医院收治的92例巨大子宫肌瘤患者作为研究对象,随机分为对照组与观察组,每组46例。对照组采用传统开腹子宫切除术,观察组采用腹腔镜辅助阴式全子宫切除术。比较两组围手术期指标、氧化应激指标[缺血修饰白蛋白(IMA)、肌红蛋白(MYO)]、视觉模拟评分法(VAS)、雌激素受体(ER)及孕激素受体(PR)水平及并发症发生率。结果观察组手术时间、肛门排气时间、下床活动时间、住院时间均短于对照组,术中出血量少于对照组,差异有统计学意义(P<0.05)。治疗后,两组IMA、MYO水平均高于治疗前,但观察组低于对照组,差异有统计学意义(P<0.05)。观察组VAS评分、ER及PR水平均低于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论腹腔镜辅助阴式全子宫切除术治疗巨大子宫肌瘤效果显著,可减少患者术中出血量,且氧化应激反应较小、并发症较少,术后可快速康复,值得临床推广应用。
Objective To explore the application value of laparoscopic assisted vaginal hysterectomy in the treatment of giant uterine fibroids.Methods A total of 92 patients with giant uterine fibroids admitted to the First People's Hospital of Ji'nan from January 2020 to February 2021 were selected as the study subjects,they were randomly divided into the control group and the observation group,with 46 cases in each group.The control group was treated with traditional open hysterectomy,and the observation group was treated with laparoscopic assisted vaginal hysterectomy.The perioperative indexes,oxidative stress indexes(ischemia modified albumin[IMA],myoglobin[MYO]),visual analogue scale(VAS),estrogen re-ceptor(ER)and progesterone receptor(PR)levels and the incidence of complications were compared between the two groups.Results The opera-tion time,anal exhaust time,ambulation time and hospitalization time in the observation group were shorter than those in the control group,and the intraoperative blood loss was less than that in the control group,the differences were statistically significant(P<0.05).After treatment,the levels of IMA and MYO in the two groups were higher than those before treatment,but the observation group was lower than the control group,the differenc-es were statistically significant(P<0.05).The VAS score,ER and PR levels in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The incidence of complications in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion Laparoscopic assisted vaginal hysterectomy is effective in the treatment of giant uterine fibroids,the patients have less intraoperative blood loss,less oxidative stress,fewer complications,and rapid recovery after surgery,and is worthy of clinical promotion and application.
作者
彭川伟
郑建伟
杨凤
PENG Chuanwei;ZHENG Jianwei;YANG Feng(Department of Obstetrics and Gynecology,the First People's Hospital of Ji'nan,Ji'nan,Shandong,251000,China;Department of Visit Yanshan Outpatient,Ji'nan Meinian Great Health Technology Co.,LTD,Ji'nan,Shandong,251000,China)
出处
《当代医学》
2023年第30期82-85,共4页
Contemporary Medicine
关键词
巨大子宫肌瘤
腹腔镜辅助阴式
全子宫切除术
Giant uterine fibroids
Laparoscopic assisted vaginal
Total hysterectomy
