摘要
过敏性疾病的发生率逐年增加,环境因素在其中起着重要作用。不同的暴露因素、膳食结构、生活环境对机体肠道菌群定植、变化产生重要影响。肠道菌群的丰度、组成、代谢产物可通过免疫、代谢、神经内分泌等途径与宿主皮肤、消化道、呼吸道等部位的免疫系统相互作用,对过敏性疾病的类型、严重程度及持续时间产生持久影响。本文主要针对肠道菌群与过敏性疾病的关系展开综述。
The incidence rate of allergic diseases is increasing year by year,and environmental factors play an important role in it.Different exposure factors,dietary structure,and living environment exert crucial effects on the colonization and change of intestinal flora in the body.The abundance,composition and metabolites of intestinal flora can interact with the host immune system in skin,digestive tract,respiratory tract,and other parts of the body through immune,metabolic,neuroendocrine,and other pathways,which exert a lasting impact on the type,severity and duration of allergic diseases.This paper reviews the relation of intestinal flora with allergic diseases.
作者
张纪泳
曾永梅
ZHANG Jiyong;ZENG Yongmei(Department of Pediatrics,Shenzhen Maternity&Child Healthcare Hospital,Shenzhen 518028,Guangdong,China)
出处
《广西医学》
CAS
2024年第1期15-19,共5页
Guangxi Medical Journal
基金
深圳市科技计划项目(JCYJ20220530155208019)
深圳市“医疗卫生三名工程”项目(SZSM202311021)。
关键词
过敏性疾病
肠道菌群
特应性皮炎
食物过敏
哮喘
综述
Allergic diseases
Intestinal flora
Atopic dermatitis
Food allergy
Asthma
Review
