摘要
马钱子碱具有抗炎镇痛、调节神经系统、抗心律失常、抗血栓、促进成骨等作用。将马钱子碱用于治疗乳腺癌、肝癌、结直肠癌等疾病的研究日益增多。现综述近年来有关马钱子碱抗肿瘤作用的研究进展。
Brucine is one of the main components derived from the dried mature seeds of Strychnos nux-vomica L.and S.Prerriana A.W.Hill.Brucine has been proved possessing many effects,such as anti-inflammatory and analgesic,regulating the nervous system,anti-arrhythmia,antithrombotic,promoting osteogenesis.It has been used in the treatment of diseases including osteoarthritis,paralysis,scabies and so on.The anti-tumor effect of brucine in diseases such as breast cancer,liver cancer,colorectal cancer and other diseases has become increasingly active.The recent research progress on the antitumor effect of brucineis reviewed.
作者
余源
黄媚娟
YU Yuan;HUANG Meijuan(West China Hospital,Sichuan University,Chengdu,Sichuan,610041 R.P.China)
出处
《华西药学杂志》
CAS
CSCD
北大核心
2024年第2期231-234,共4页
West China Journal of Pharmaceutical Sciences
基金
四川大学华西医院临床研究孵化项目重点项目(2021HXFH055)。
关键词
马钱子碱
马钱
云南马钱
抗肿瘤
肝癌
三阴性乳腺癌
肺癌
结肠癌
多发性骨髓瘤
研究进展
Brucine
Strychnos nux-vomica
S.PrerrianaAnticancer
Hepatocarcinoma
Triple-negative breast cancer
Lung cancer
Colon cancer
Multiple myeloma
Research progress
