摘要
目的:观察右美托咪定复合罗哌卡因腹横肌平面阻滞(TAPB)在腹膜透析置管术患者中的应用效果。方法:选取2019年2月至2021年2月于该院行腹膜透析置管术的101例患者进行前瞻性研究,按照随机数字表法将其分为对照组(n=50)和观察组(n=51)。对照组采用罗哌卡因TAPB,观察组采用右美托咪定复合罗哌卡因TAPB。比较两组麻醉相关指标(麻醉起效时间、麻醉持续时间)水平,术后2、4、6 h疼痛[视觉模拟评分法(VAS)]、镇静(Ramsay评分法)评分,手术前后应激指标[皮质醇(Cor)、去甲肾上腺素(NE)、肾上腺素(E)]水平,以及不良反应发生率。结果:观察组麻醉起效时间短于对照组,麻醉持续时间长于对照组,差异有统计学意义(P<0.05);术后2、4、6 h,观察组VAS评分均低于对照组,Ramsay评分均高于对照组,差异有统计学意义(P<0.05);术后,观察组Cor、E、NE水平均低于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:右美托咪定复合罗哌卡因TAPB应用于腹膜透析置管术患者可改善麻醉相关指标水平,降低术后疼痛评分和应激指标水平,提高术后镇静评分,效果优于单纯罗哌卡因TAPB。
Objective:To observe application effects of Dexmedetomidine combined with Ropivacaine transversus abdominis plane block(TAPB)in patients undergoing peritoneal dialysis catheterization.Methods:A prospective study was conducted on 101 patients who underwent peritoneal dialysis catheterization in the hospital from February 2019 to February 2021.According to the random number table method,they were divided into control group(n=50)and observation group(n=51).The control group was treated with Ropivacaine TAPB,while the observation group was treated with Dexmedetomidine combined with Ropivacaine TAPB.The levels of anesthesia-related indicators(onset time and duration of anesthesia),the pain[visual analogue scale(VAS)]score,and the sedation(Ramsay score)scores at 2,4,6 h after the surgery,the stress indicator levels[cortisol(Cor),norepinephrine(NE),epinephrine(E)]before and after the surgery,and the incidence of adverse reactions were compared between the two groups.Results:The onset time of anesthesia in the observation group was shorter than that in the control group,the duration was longer than that in the control group,and the differences were statistically significant(P<0.05).2,4,6 h after the surgery,the VAS scores of the observation group were lower than those of the control group,the Ramsay scores were higher than those of the control group,and the differences were statistically significant(P<0.05).After the surgery,the levels of Cor,E and NE in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Dexmedetomidine combined with Ropivacaine TAPB in the patients undergoing peritoneal dialysis catheterization can improve the levels of anesthesia-related indicators,reduce the postoperative pain scores and the stress indicator levels,and improve the postoperative sedation scores.Moreover,it is superior to single Ropivacaine T
作者
年春苗
田丹丹
付琦
郭海明
NIAN Chunmiao;TIAN Dandan;FU Qi;GUO Haiming(Department of Anesthesia and Perioperative Medicine of the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000 Henan,China)
出处
《中国民康医学》
2024年第7期65-67,共3页
Medical Journal of Chinese People’s Health
关键词
右美托咪定
罗哌卡因
腹横肌平面阻滞
腹膜透析置管术
疼痛
应激
镇静
Dexmedetomidine
Ropivacaine
Transversus abdominis plane block
Peritoneal dialysis catheterization
Pain
Stress
Sedation
