摘要
目的探讨彩色多普勒超声结合血清D-二聚体(D-D)对下肢深静脉血栓形成后综合征(PTS)的评估价值。方法选取2019年3月~2022年5月本院收治的147例疑似PTS患者,均进行彩色多普勒超声检查和血清D-D水平检测。以下肢静脉造影结果为“金标准”,分析彩色多普勒超声和血清D-D单独及联合对PTS的评估价值。结果147例疑似PTS患者经下肢静脉造影确诊102例;PTS患者的病变血管内径、血管内膜异常占比、瓣膜功能异常占比和血清D-D水平均高于非PTS患者(P<0.05),PTS患者的血流速度低于非PTS患者(P<0.05);经Kappa一致性检验发现,彩色多普勒超声和血清D-D单独及联合评估PTS与“金标准”的一致性高(Kappa=0.880、0.851、0.978,P<0.001);彩色多普勒超声和血清D-D联合评估PTS的灵敏度、准确度、阴性预测值均高于单独评估(P<0.05),特异度、阳性预测值与单独评估差异无统计学意义(P>0.05)。结论彩色多普勒超声结合血清D-D诊断PTS的灵敏度和准确度较高,对PTS具有良好的评估价值。
Objective To explore the value of color doppler ultrasound combined with serum D-dimer(D-D)in the evaluation of post-thromboemblic syndrome in lower extremity deep vein(PTS).Methods 147 suspected PTS patients admitted to our hospital from March 2019 to May 2022 were selected,and they were examined by color Doppler ultrasound,and the serum D-D levels of them were detected.Taking the results of lower limb phlebography as the"gold standard",the evaluation value of color doppler ultrasound and serum D-D alone and joint for PTS were analyzed.Results 102 cases of 147 suspected PTS patients were confirmed by lower extremity venography.The diameter of diseased vessels,the proportion of abnormal vascular intima,the proportion of abnormal valve function and the serum D-D level in PTS patients were higher than those in non PTS patients(P<0.05),and the blood flow velocity in PTS patients was lower than that in non PTS patients(P<0.05).Kappa consistency test showed that the consistency of PTS evaluated by color doppler ultrasound and serum D-D alone and joint were high with the"gold standard"(Kappa=0.880,0.851,0.978,P<0.001).The sensitivity,accuracy and negative predictive value of the combined evaluation of color doppler ultrasound and serum D-D for PTS were higher than those of the single evaluation(P<0.05),while the specificity and positive predictive value had no statistical significance(P>0.05).Conclusion The sensitivity and accuracy of color doppler ultrasound combined with serum D-D in the diagnosis of PTS are high,and it has good evaluation value for PTS.
作者
周莹
刘花艳
刘金阁
ZHOU Ying;LIU Hua-yan;LIU Jin-ge(Department of Ultrasound,The First People's Hospital of Xinxiang,Xinxiang 453000,Henan Province,China)
出处
《罕少疾病杂志》
2024年第4期115-117,共3页
Journal of Rare and Uncommon Diseases
