摘要
目的为了深入研究对脑损伤新生儿实施早期干预和营养脑细胞治疗后,患儿NBNA评分、胆红素不同形态监测水平、留院观察指标、不良反应控制情况及发育情况。方法选取我院2021年11月至2022年11月期间收治的脑损伤新生儿共100例,给予早期干预和营养脑细胞治疗措施组为研究组,给予常规治疗和护理措施组为参照组,研究组和参照组各50例患儿。对比两组患儿NBNA评分、胆红素不同形态监测水平、留院观察指标、不良反应控制情况及发育情况。结果干预期结束后,NBNA评分:干预后,研究组NBNA评分为(39.35±6.88),参照组NBNA评分为(36.44±6.55),研究组NBNA评分显著较优;胆红素不同形态监测水平:研究组直接胆红素水平为(20.14±14.32),间接胆红素水平为(191.26±63.01),总胆红素水平为(225.53±683.22),参照组直接胆红素水平为(30.23±15.74),间接胆红素水平为(247.15±78.02),总胆红素水平为(267.15±93.13),研究组胆红素不同形态监测水平显著较优;留院观察指标:研究组胆红素每天降低的幅度为(58.13±12.42),退黄时间(4.13±0.53),平均留院观察时间(6.53±1.27),参照组胆红素每天降低的幅度为(51.14±10.25),退黄时间(6.63±0.92),平均留院观察时间(8.14±1.77),研究组留院观察指标显著较优;不良反应控制情况:研究组发生率为%,参照组发生率为%,研究组不良反应控制情况显著优于参照组;发育情况:研究组抬头评分为(3.72±1.13),翻身评分为(4.24±1.39),独坐评分为(4.18±1.15),爬评分为(6.35±1.34),参照组抬头评分为(3.72±1.13),翻身评分为(4.24±1.39),独坐评分为(4.18±1.15),爬评分为(6.35±1.34),研究组发育情况显著较优,(P<0.05)。结论临床对脑损伤新生儿实施早期干预和营养脑细胞治疗,可有效改善患儿NBNA评分、胆红素不同形态监测水平、留院观察指标、不良反应控制情况及发育情况,故方案值得推广。
Objective To study the NBNA score,monitoring level of different forms of bilirubin,hospital observation index,adverse reaction control and development of neonates with brain injury after early intervention and brain cell therapy.Methods A total of 100 neonates with brain injury who were admitted to our hospital from November 2021 to November 2022 were selected,and the group given early intervention and nutritional brain cell therapy measures was selected as the study group,and the group given conventional treatment and nursing measures were given as the reference group,and 50 children were treated in the study group and the reference group.The NBNA score,monitoring level of different forms of bilirubin,observation indexes,control of adverse reactions and development of the two groups were compared.Results After the intervention period,the NBNA score was(39.35±6.88)in the study group and(36.44±6.55)in the reference group.The levels of bilirubin were(20.14±14.32),(191.26±63.01),(225.53±683.22)in the study group,(30.23±15.74),(247.15±78.02)and(267.15±93.13)in the control group.The monitoring level of different forms of bilirubin in the study group was significantly better.Observation indexes:the daily decrease of bilirubin in the study group was(58.13±12.42),the time of yellowing(4.13±0.53),the average time of hospitalization(6.53±1.27),the daily decrease of bilirubin in the control group was(51.14±10.25),the time of yellowing(6.63±0.92),and the average duration of hospitalization(8.14±1.77).Control of adverse reactions:the incidence of adverse reactions in the study group was%,the incidence of the reference group was%,and the control of adverse reactions in the study group was significantly better than that in the control group;Development:The head-up score of the study group was(3.72±1.13),the roll-over score was(4.24±1.39),the solitary sitting score was(4.18±1.15),the climbing score was(6.35±1.34),the head-up score of the control group was(3.72±1.13),the turn-over score was(4.24±1.39),the soli
作者
王书磊
WANG Shu-lei(NICU,Pingdingshan First People’s Hospital Pingdingshan 467000,Henan Province,China)
出处
《罕少疾病杂志》
2024年第4期19-20,共2页
Journal of Rare and Uncommon Diseases
关键词
早期新生儿神经学评分
脑损伤新生儿
治疗影响
Early Neonatal Neurological Score
Newborns with Brain Injury
Therapeutic Effects
