摘要
目的观察早期针刺辅助治疗新生儿脑损伤综合征的临床疗效。方法选取2016年1月-2018年1月西安市儿童医院收治的新生儿脑损伤综合征患儿96例,随机分为对照组和观察组,每组48例。对照组患儿给予康复训练联合药物治疗,观察组患儿在对照组治疗基础上给予早期针刺辅助治疗;两组患儿均连续治疗3个月。比较两组患儿临床疗效,治疗前后Gesell发育诊断量表(GDDS)、智力发育指数(MDI)、运动发育指数(PDI)、新生儿行为神经测定(NBNA)评分及肌张力;随访6个月,记录两组患儿脑瘫发生率。结果(1)观察组患儿临床疗效优于对照组(P<0.05)。(2)两组患儿治疗前适应性行为、个人-社交行为、大运动行为、精细动作行为及语言行为的发育商(DQ)比较,差异无统计学意义(P>0.05);观察组患儿治疗后适应性行为、个人-社交行为、大运动行为、精细动作行为及语言行为的DQ高于对照组(P<0.05)。(3)两组患儿治疗前MDI、PDI、NBNA评分比较,差异无统计学意义(P>0.05);观察组患儿治疗后MDI、PDI、NBNA评分高于对照组(P<0.05)。(4)两组患儿治疗前肌张力比较,差异无统计学意义(P>0.05);观察组患儿治疗后肌张力优于对照组(P<0.05)。(5)观察组患儿随访期间脑瘫发生率低于对照组(P<0.05)。结论早期针刺辅助治疗新生儿脑损伤综合征的临床疗效确切,能有效改善患儿中枢神经系统功能,促进患儿神经、智力及运动发育,降低脑瘫发生风险。
Objective To observe the clinical effect of early acupuncture treatment in the adjuvant therapy of neonatal brain injury syndrome. Methods A total of 96 children with neonatal brain injury syndrome were selected in Children’s Hospital of Xi’an from January 2016 to January 2018,and they were randomly divided into control group and observation group,with 48 cases in each group. Children in control group received rehabilitation training combined with drug therapy,while children in observation group received early acupuncture treatment as adjuvant therapy based on that of control group;both groups continuously treated for 3 months. Clinical effect,pre-and post-treatment Gesell Development Diagnosis Scale(GDDS)results,Mental Development Index(MDI),Physical Development Index(PDI),Neonatal Behavioral Nerve Assay(NBNA)score and muscular tension were compared between the two groups;incidence of cerebral palsy was observed during the 6-month follow-up. Results(1)Clinical effect in observation group was statistically significantly better than that in control group(P<0.05).(2)No statistically significant difference of development quotient(DQ)of adaptive behavior,personal-social behavior,gross motor behavior,fine motor behavior or speech act was found between the two groups before treatment(P>0.05),while DQ of adaptive behavior,personal-social behavior,gross motor behavior,fine motor behavior and speech act in observation group was statistically significantly higher than that in control group after treatment(P<0.05).(3)No statistically significant difference of MDI,PDI or NBNA score was found between the two groups before treatment(P>0.05),while MDI,PDI and NBNA score in observation group were statistically significantly higher than those in control group after treatment(P<0.05).(4)No statistically significant difference of muscular tension was found between the two groups beforetreatment(P>0.05),while muscular tension in observation group was statistically significantly better than that in control group after treatment(P
作者
史永强
江彬
史航宇
董新亚
米伟阳
SHI Yongqiang;JIANG Bin;SHI Hangyu;DONG Xinya;MI Weiyang(Department of Neurosurgery,Children's Hospital of Xi'an,Xi'an 710003,China)
出处
《实用心脑肺血管病杂志》
2019年第4期69-72,共4页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词
脑损伤综合征
新生儿
针刺疗法
神经发育
智力
运动
Brain injury syndrome
Neonate
Acupuncture therapy
Neurodevelopment
Intelligence
Exercise