摘要
目的探究多层螺旋CT(MSCT)在孤立性肺结节良恶性鉴别诊断价值。方法选取河南科技大学附属许昌市中心医院2021年1月至2023年1月收入孤立性肺结节总计72例,所有患者入院后均接受常规CT及MSCT检查,并以病理检查结果作为诊断金标准,分析MSCT在孤立性肺结节诊断效能以及良性结节与恶性结节CT征象特征。结果72例孤立性结节患者经病理检查,结果显示良性结节51例(70.83%)、恶性结节21例(29.17%)。MSCT的诊断准确率、特异性(93.06%、94.12%),高于常规CT(79.17%、80.39%),差异有统计学意义(P<0.05);恶性结节中钙化(14.29%)低于良性结节(39.22%),恶性结节中分叶征、毛刺征、胸膜凹陷征(85.71%、76.19%、71.43%),高于良性结节(13.73%、15.69%、7.84%),差异有统计学意义(P<0.05),而良性结节与恶性结节在空泡征对比差异无统计学意义(P>0.05);恶性结节中常规CT、MSCT中定量参数增强峰值(PH)、孤立性肺结节与主动脉强化峰值的比值(S_(PH)/A_(PH))均高于良性结节,差异有统计学意义(P<0.05)。结论MSCT应用于孤立性肺结节良恶性鉴别诊断中具有较高准确性,同时良恶性结节CT征象上差异显著,为临床早期鉴别诊断提供合理依据,医师能依据诊断结果制定出合理治疗方案。
Objective To explore the diagnostic value of multi-slice CT(MSCT)in the differential diagnosis of benign and malignant solitary pulmonary nodules.Methods A total of 72 patients with solitary pulmonary nodules admitted to Xuchang Central Hospital affiliated with Henan University of Science and Technology from January 2021 to January 2023 were selected.All patients underwent routine CT and MSCT examinations after admission,and the pathological examination results were used as the diagnostic gold standard.The diagnostic efficacy of MSCT in solitary pulmonary nodules and the CT features of benign and malignant nodules were analyzed.Results After pathological examination,72 patients with solitary nodules were found to have 51 benign nodules(70.83%)and 21 malignant nodules(29.17%).The diagnostic accuracy and specificity of MSCT(93.06%,94.12%)were higher than those of conventional CT(79.17%,80.39%),and the difference was statistically significant(P<0.05);Calcification in malignant nodules(14.29%)was lower than that in benign nodules(39.22%),while lobulation sign,spiculation sign,and pleural depression sign in malignant nodules(85.71%,76.19%,71.43%)were higher than those in benign nodules(13.73%,15.69%,7.84%),with statistically significant differences(P<0.05).However,there was no statistically significant difference in vacuolar sign between benign nodules and malignant nodules(P>0.05);The ratio of peak enhanced parameters(PH)in conventional CT and MSCT,as well as the ratio of peak enhanced parameters(S_(PH)/A_(PH))between solitary pulmonary nodules and aortic enhancement in malignant nodules,were higher than those in benign nodules,with statistical significance(P<0.05).Conclusion The application of MSCT in the differential diagnosis of benign and malignant solitary pulmonary nodules has high accuracy,and there are significant differences in CT signs between benign and malignant nodules,providing a reasonable basis for early clinical differential diagnosis.Physicians can develop a reasonable treatment plan based on the di
作者
朱莉莉
赵宜
ZHU Lili;ZHAO Yi(Health Management Center,Xuchang Central Hospital affiliated with Henan University of Science and Technology,Xuchang Henan 461000,China;Department of Respiratory,Xuchang Central Hospital Affiliated to Henan University of Science and Technology,Xuchang Henan 461000,China)
出处
《临床研究》
2024年第4期30-33,共4页
Clinical Research
关键词
多层螺旋CT
孤立性肺结节
良恶性
鉴别诊断
multi-slice CT
solitary pulmonary nodules
benign and malignant
differential diagnosis