摘要
目的分析伴非自杀性自伤(non-suicidal self-injury,NSSI)行为青少年抑郁障碍患者睡眠情况与认知功能的关联。方法选取某精神专科医院门诊就诊的青少年抑郁障碍患者共100例,依据有无NSSI行为,使用汉密尔顿抑郁量表(HAMD-17)评估抑郁程度;以中国简版神经认知成套测验(C-BCT)评估认知功能;使用匹兹堡睡眠质量指数量表(PSQI)评估睡眠情况;比较两组患者相关量表及测试得分的差异,并分析NSSI组患者认知功能与睡眠情况的相关性。结果两组一般资料差异无统计学意义(P>0.05),NSSI组HAMD-17(P<0.01)、PSQI评分(P<0.05)高于非NSSI组,NSSI组C-BCT测试(P<0.05)评分低于非NSSI组。多元线性回归分析显示,日间功能障碍对信息处理速度有显著的影响(B=-1.081,P<0.05);睡眠时间对注意力(B=-4.099,P<0.01)、工作记忆力(B=-2.472,P<0.05)、综合+执行功能(B=-3.103,P<0.05)有显著影响;睡眠障碍对工作记忆力(B=-3.169,P<0.05)有显著影响;睡眠质量对综合+执行能力(B=-8.604,P<0.01)有显著影响。二元Logistics回归分析表明,睡眠时间不足是注意力的风险因素(OR=11.572,P<0.01),睡眠效率下降是工作记忆力的风险因素(OR=2.160,P<0.05)。结论伴NSSI行为的青少年抑郁障碍患者认知功能及睡眠情况受损更严重,认知功能与睡眠情况存在相关性,其中日间功能障碍、睡眠时间、睡眠障碍及睡眠质量是认知功能的影响因素。
Objective To analyze the association between cognitive function and sleep in adolescent depressive disorder patients with non-suicidal self-injury(NSSI)behavior.Methods A total of 100 patients with adolescent de-pressive disorder who attended our outpatient clinic from December 2021 to January 2023 were selected and divided into NSSI and non-NSSI groups based on the presence or absence of NSSI behaviors;the same scales and tests were evalu-ated to individuals in both groups,and general information was compared using the self-made clinical characteristics information table.The degree of depression was assessed using the Hamilton Depression Inventory(HAMD-17).Cog-nitive function was assessed by the Chinese Brief Neurocognitive Test(C-BCT).Sleep was assessed by the Pittsburgh Sleep Quality Index(PSQI).The differences in the scores of relevant scales and tests between the two groups were com-pared,and the correlation between cognitive function and sleep in the NSSI group was analyzed.Results The differ-ences in general information between the two groups were not statistically significant(P>0.05).HAMD-17(P<0.01)and PSQI scores(P<0.05)were higher in the NSSI group than in the non-NSSI group,and C-BCT test score scores(P<0.05)were lower in the NSSI group than in the non-NSSI group.Multiple linear regression analysis showed that daytime dysfunction had a significant effect on information processing speed(B=-1.081,P<0.05).Sleep duration had a significant effect on attention(B=-4.099,P<0.01),working memory(B=-2.472,P<0.05),and comprehensive abilities with executive function(B=-3.103,P<0.05).Sleep disturbance had a significant effect on working memory(B=-3.169,P<0.05).And sleep quality had a significant effect on comprehensive abilities with executive func-tion(B=-8.604,P<0.01).Binary Logistics regression analysis showed that lack of sleep is risk factor for attention(OR=11.572,P<0.01).Decreased sleep efficiency is risk factor for working memory(OR=2.160,P<0.05).Con-clusion Cognitive function and sleep status were more seve
作者
王璐
韩海斌
刘洁
王婷婷
贾雪瑜
WANG Lu;HAN Haibin;LIU Jie(Qingdao Mental Health Center,Qingdao 266100,China)
出处
《国际精神病学杂志》
2024年第1期95-99,107,共6页
Journal Of International Psychiatry
基金
山东省医药卫生科技发展计划项目(编号:2018WS367)。
关键词
非自杀性自伤
抑郁障碍
认知功能
睡眠
Non-suicidal self-injury
Depressive disorder
Cognitive function
Sleep
