摘要
目的 探究云南省动物源性食品鸡肉、鸡蛋中尼卡巴嗪、地克珠利、托曲珠利、托曲珠利砜4种抗球虫药物残留的状况及食用风险。方法 2022年3—5月采集云南16个州市128件样品,采用高效液相色谱质谱法监测鸡肉、鸡蛋中4种抗球虫药物尼卡巴嗪、地克珠利、托曲珠利、托曲珠利砜残留量,并依据每日摄入量进行风险评估。结果 鸡肉、鸡蛋中均有检出,检出浓度范围为1.00~296μg/kg,尼卡巴嗪、地克珠利、托曲珠利及托曲珠砜利最大残留含量分别为210、115、296和1.00μg/kg,2份样品超标,超标率为1.56%。估算每日风险暴露量鸡肉为0.016 9μg/(kg×bw),鸡蛋为0.004 93μg/(kg×bw),远低于每日容许摄入量。结论 虽然云南省鸡肉、鸡蛋摄入不会对人体健康产生食用风险,但食用鸡肉、鸡蛋时抗球虫药物的摄入应引起关注。
Objective To explore the residual status and consumption risks of four anti coccidiosis drugs,namely nicarbazine,diclazulide,tocracolizumab,and tocracolizumab sulfone,in animal derived foods such as chicken and eggs in Yunnan Province.Methods A total of 128 samples were collected from 16 cities in Yunnan Province from March to May 2022,high performance liquid chromatography-mass spectrometry(LC-MS)was used to monitor the residual levels of four anticoccidia drugs,including nicarbizine,desculide,totrozulide and totrozulide in chicken and eggs,and the risk was assessed according to daily intake.Results It was detected in both chicken and egg,and the detection concentration ranged from 1.00 to 296μg/kg,the maximum residue levels of nicarbazide,diclazuril,toltrazuril sulfone,and toltrazuril were 210,115,296,and 1.00μg/kg,respectively,with the over-standard rate was 1.56%(2 cases).The estimated daily risk exposure was 0.0169μg/(kg·bw)for chicken and 0.00493μg/(kg·bw)for eggs,which was well below the allowable daily intake(ADI).Conclusion The intake of chicken and eggs in Yunnan Province does not pose a risk to human health,but attention should be paid to the intake of anti coccidiosis drugs when consuming chicken and eggs.
作者
杜凤龄
钟姣
秦光河
栾杰
DU Fengling;ZHONG Jiao;QIN Guanghe;LUAN Jie(Health Physical and Chemical Testing Center,Wenshan Prefecture Disease Prevention and Control Center,Wenshan Yunnan,663099,China;Health Physical and Chemical Testing Center,Yunnan Center for Disease Control and Prevention,Kunming Yunnan,650022,China)
出处
《职业与健康》
CAS
2024年第2期200-204,共5页
Occupation and Health
关键词
抗球虫药物
鸡肉
鸡蛋
高效液相色谱串联质谱法
Anticoccidian drugs
Chicken
Eggs
High Performance liquid chromatography tandem mass spectrometry
