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六味地黄丸联合二甲双胍片治疗2型糖尿病的临床疗效分析

Clinical Efficacy of Liuwei Dihuang Pill Combined with Metformin Tablet in Treatment of Type 2 Diabetes Mellitus
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摘要 目的 探究临床上为2型糖尿病患者联合运用二甲双胍片与六味地黄丸进行治疗的实际效果。方法 选取2022年3月—2023年2月仙游县妇幼保健院陆续收治的2型糖尿病患者60例为研究对象,遵循组件样本特征存在可比性的前提下运用随机双色球法将上述患者分为对比组与探究组,各30例。对比组采用二甲双胍片治疗,而探究组联合运用二甲双胍片与六味地黄丸治疗。对比两组患者治疗前后的血糖水平、临床疗效、治疗期间不良反应发生率以及治疗后生活质量评分。结果 治疗前,两组糖化血红蛋白、空腹血糖、餐后2 h血糖等指标比较,差异无统计学意义(P均>0.05);治疗后,探究组糖化血红蛋白、空腹血糖、餐后2 h血糖等指标均低于对比组,差异有统计学意义(P均<0.05)。探究组临床疗效高于对比组,差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。治疗后,探究组总体健康、情感职能、生命活力、精神健康等维度的生活质量评分均高于对比组,差异有统计学意义(P均<0.05)。结论 在临床上联合运用二甲双胍片与六味地黄丸为2型糖尿病患者实施治疗可取得显著效果,既能够促使患者的血糖水平获得有效控制,又可使患者的生活质量获得一定程度的提升,同时也具有较好的安全性。 Objective To explore the clinical effect of combined use of metformin tablets and Liuwei Dihuang pills in the treatment of type 2 diabetes.Methods 60 patients with type 2 diabetes who were admitted to Xianyou County Ma-ternal and Child Health Hospital from March 2022 to February 2023 were selected as the study objects.Based on the premise of comparability of component sample characteristics,the patients were divided into comparison group and an exploration group with 30 cases in each group by random bicolor method.The comparison group was treated with met-formin tablets,while the exploration group was treated with metformin tablets and Liuwei Dihuang pills.Blood glucose level,clinical efficacy,incidence of adverse reactions during treatment and quality of life score after treatment were compared between the two groups.Results Before treatment,there was no statistically significant difference in gly-cated hemoglobin,fasting blood glucose and 2-hour postprandial blood glucose between the two groups(all P>0.05).After treatment,the indexes of glycated hemoglobin,fasting blood glucose and 2-hour postprandial blood glucose in the exploration group were lower than those in the comparison group,and the differences were statistically significant(all P<0.05).The clinical efficacy of the exploration group was higher than that of the comparison group,and the differ-ence was statistically significant(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).After treatment,the life quality scores of general health,emotional func-tion,vital vitality and mental health in the exploration group were higher than those in the control group,and the dif-ferences were statistically significant(all P<0.05).Conclusion The combined application of metformin tablets and Liu-wei Dihuang pills for the clinical treatment of type 2 diabetes patients can achieve remarkable results,which can not only effectively control the blood glucose level of patients,but also improve the q
作者 徐慧白 林智勇 黄慧贞 XU Huibai;LIN Zhiyong;HUANG Huizhen(Department of Internal Medicine,Xianyou County Maternal and Child Health Hospital,Xianyou,Fujian Province,351200 China;Department of Traditional Chinese Medicine,Xianyou County Maternal and Child Health Hospital,Xianyou,Fujian Province,351200 China)
出处 《糖尿病新世界》 2024年第2期80-82,86,共4页 Diabetes New World Magazine
关键词 二甲双胍片 六味地黄丸 2型糖尿病 Metformin tablets Liuwei Dihuang pill Type 2 diabetes
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