摘要
目的探索济南市发热伴血小板减少综合征发病的危险因素,为防控提供参考依据。方法采用病例对照研究方法,将2014—2022年济南市发热伴血小板减少综合征确诊患者纳入病例组,按比例选择病例发病同期居住地附近的健康居民为对照组,收集相关资料,运用单因素和多因素logistic回归分析危险因素。结果本研究共纳入632例确诊病例和1571例健康居民,多因素logistic回归分析显示,被蜱虫叮咬(OR=153.123,95%CI:14.069~1666.532)、从事田间作业(OR=3.948,95%CI:1.019~15.298)、工作周边环境有杂草/灌木(OR=3.603,95%CI:1.204~10.785)、田间有蜱虫(OR=3.120,95%CI:1.071~9.089)是发热伴血小板减少综合征发病的危险因素;田间作业采取防护措施(OR=0.193,95%CI:0.080~0.465)和周边亲邻发病(OR=0.003,95%CI:0.000~0.025)是发热伴血小板减少综合征发病的保护因素。结论被蜱虫叮咬、从事田间作业、工作周边环境有杂草/灌木、田间有蜱虫是发热伴血小板减少综合征发病的主要危险因素,应加强高风险人员健康教育及行为干预,预防和控制发热伴血小板减少综合征的发病。
Objective To explore the risk factors for onset of severe fever with thrombocytopenia syndrome(SFTS)in Jinan City,and to provide a reference basis for prevention and control of the disease.Methods Case-control study method was used to enroll confirmed patients with SFTS in Jinan City during 2014-2022 into the case group,and healthy residents living near the patients’residence in the same period were selected proportionally as the control group.Their related data were collected.Univariate and multivariable logistic regression analyses were performed to identify risk factors.Results A total of 632 SFTS cases and 1,571 healthy residents were enrolled into this study.Multivariable logistic regression analysis revealed that tick bite history(OR=153.123,95%CI:14.069-1,666.532),engaging in field work(OR=3.948,95%CI:1.019-15.298),having weeds/shrubs around working areas(OR=3.603,95%CI:1.204-10.785)and having ticks in the field(OR=3.120,95%CI:1.071-9.089)were risk factors for SFTS onset(P<0.05).Taking protective measures in field operations(OR=0.193,95%CI:0.080-0.465)and having family members or neighbors with SFTS(OR=0.003,95%CI:0.000-0.025)were protective factors for SFTS onset(P<0.05).Conclusion Tick bite history,engaging in field work,having weeds and shrubs around working areas and having ticks in the field are main risk factors for SFTS onset.Health education and behavioral interventions should be strengthened in the high-risk population so as to prevent and control SFTS onset.
作者
高尚
任娅如
单朝霞
常彩云
GAO Shang;REN Yaru;SHAN Zhaoxia;CHANG Caiyun(Jinan Municipal Center for Disease Control and Prevention,Jinan,Shandong 250021,China;The First Affiliated Hospital of Shandong First Medical University(Shandong Provincial Qianfoshan Hospital),Jinan,Shandong 250014,China)
出处
《实用预防医学》
CAS
2024年第2期169-172,共4页
Practical Preventive Medicine
基金
济南市卫健委科技发展计划项目(2023-公-18)。
关键词
发热伴血小板减少综合征
病例对照
危险因素
severe fever with thrombocytopenia syndrome
case-control study
risk factor
