摘要
目的 探讨临床中治疗后循环缺血性眩晕时采用川芎嗪注射液联合倍他司汀的临床效果。方法 随机选取2021年1月—2022年12月泉州市光前医院收治的100例后循环缺血性眩晕患者为研究对象,根据治疗方法的不同分为参照组和研究组。参照组(50例)单独使用倍他司汀治疗,研究组(50例)川芎嗪注射液联合倍他司汀治疗。对比两组治疗前后的临床指标。结果 研究组总有效率为94.00%,明显高于参照组的80.00%,差异有统计学意义(χ^(2)=4.332,P<0.05);治疗前,两组椎-基底动脉流速比较,差异无统计学意义(P>0.05);治疗后,两组的左椎-基底动脉流速升高,且研究组高于参照组,差异有统计学意义(P均<0.05);治疗前,两组眩晕症状评分比较,差异无统计学意义(P>0.05);治疗后,两组眩晕症状评分均降低,且研究组眩晕症状评分[(14.26±6.09)分]低于参照组[(18.33±5.27)分],差异有统计学意义(P<0.05);治疗前,两组血液流变学指标比较,差异无统计学意义(P>0.05);治疗后,两组血液流变学指标均得到改善,且研究组优于参照组,差异有统计学意义(P均<0.05)。两组的不良反应发生率比较,差异无统计学意义(P>0.05)。结论 临床中采用川芎嗪注射液联合倍他司汀治疗后循环缺血性眩晕,疗效显著,可有效改善患者的椎-基底动脉流速,改善眩晕症状和血液流变学指标,且不良反应较少。
Objective To investigate the clinical effect of ligustrazine injection combined with betahistine in the treatment of post-circulation ischemic vertigo.Methods 100 patients with posterior circulatory ischemic vertigo,admitted to Quanzhou Guangqian Hospital from January 2021 to December 2022,were randomly selected as the study objects and divided into reference group and study group according to different treatment methods.The reference group(50cases) was treated with betaetine alone,and the study group(50 cases) was treated with ligutizine injection combined with betaetine.Compared the clinical indicators before and after treatment between the two groups.Results The total effective rate of the study group was 94.00%,which was significantly higher than 80.00% of the reference group,and the difference was statistically significant(χ^(2)=4.332,P<0.05).Before treatmen,there was no statistically significant difference in vertebra-basilar artery flow rate between the two groups(P>0.05).After treatment,the left vertebrabasilar artery flow rate increased in two groups and was increased,and the study group was higher than the reference group,and the differences were statistically significant(both P<0.05).Before treatment,there was no statistically significant difference in Vertigo Symptom Score between the two groups(P>0.05).After treatment,the Vertigo Symptom Score decreased,and the Vertigo Symptom Score in the study group [(14.26±6.09) points] was lower than that in the reference group [(18.33±5.27) points],and the differences were statistically significant(both P<0.05).Before treatment,there was no statistically significant difference in hemorheological indexes between the two groups(P>0.05).After treatment,hemorheology indexes were improved,and the study group was better than the reference group,and the differences were statistically significant(both P<0.05).There was no statistically significant difference in adverse reaction between the two groups(P>0.05).Conclusion In clinical practice,when ligustrazine injection
作者
林永强
庄碧如
苏建民
LIN Yongqiang;ZHUANG Biru;SU Jianmin(Department of Neurology,Quanzhou Guangqian Hospital,Quanzhou,Fujian Province,362321 China)
出处
《中外医疗》
2023年第36期113-117,共5页
China & Foreign Medical Treatment
关键词
后循环缺血
眩晕
川芎嗪
椎-基底动脉
Posterior circulation ischemia
Vertigo
Ligustrazine
Vertebra-basilar artery
